70-265-0

Tocris Bioscience™ Veliparib dihydrochloride

Manufacturer: Tocris Bioscience™

CAS Number: 912445-05-7

Select a Size

Pack Size SKU Availability Price
Each of 1 70-265-0-Each-of-1 In Stock ₹ 16,427.52

70-265-0 - Each of 1

₹ 16,427.52

In Stock

Quantity

1

Base Price: ₹ 16,427.52

GST (18%): ₹ 2,956.954

Total Price: ₹ 19,384.474

Chemical Name or Material

2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride

Quantity

50 mg

Purity

98%

CAS

912445-05-7

Molecular Formula

C13H16N4O.2HCl

Other Options

Image Product Name Manufacturer Price Range
50-249-1332
eMolecules​ Medchem Express / Veliparib (dihydrochloride) / 5mg / 446256704 / HY-10130 / / 912445-05-7 / MFCD16661206 / 317.210 / C13H18Cl2N4O
eMolecules​ ₹ 7,556.66
AD12688
912445-05-7 | Abt-888
A2B Chem ₹ 3,422.40 - ₹ 55,870.68

Related Products

Img

Fischer Scientific

7161638

High affinity and selective histami...

Img

Fischer Scientific

76-285-0

--

Img

Fischer Scientific

7161613

Very high affinity vasopressin V1A ...

Img

Fischer Scientific

76-281-0

--

Img

Fischer Scientific

7161630

Negative control for GSK 6853...

Img

Fischer Scientific

7249489

Potent and selective A3 adenosine r...

Img

Fischer Scientific

7199105

Highly potent and selective ROCK 2 ...

Img

Fischer Scientific

74-825-0

--

Description

  • Veliparib dihydrochloride is a high affinity PARP-2 and PARP-1 inhibitor (Ki values are 2.9 and 5.2 nM, respectively)
  • Inhibits repair of radiation-induced DNA damage and sensitizes lung cancer cells to radiation
  • Also increases autophagy and apoptosis in lung cancer cells
  • Enhances radiation-induced tumor growth delay in mice bearing lung tumor xenografts
  • Also chemosensitizer
  • Potentiates effects of temozolomide (Cat
  • No
  • 2706) in a mouse melanoma model
  • Orally bioavailable and brain penetrant.

Compare Similar Items

Show Difference

Img

Tocris Bioscience™

70-265-0

--


Chemical Name or Material:
2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride

Quantity:
50 mg

Purity:
98%

CAS:
912445-05-7

Molecular Formula:
C13H16N4O.2HCl

Img

Invitrogen

70-266-9

--


Chemical Name or Material:
__

Quantity:
100 μg

Purity:
__

CAS:
__

Molecular Formula:
__

Img

Invitrogen

70-267-0

--


Chemical Name or Material:
__

Quantity:
100μg

Purity:
__

CAS:
__

Molecular Formula:
__

Img

Invitrogen

70-271-3

--


Chemical Name or Material:
__

Quantity:
100 μg

Purity:
__

CAS:
__

Molecular Formula:
__