76-442
Tocris Bioscience™ FHT 1015
Manufacturer: Tocris Bioscience™
CAS Number: 2368903-18-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 76-442-Each-of-1 | In Stock | ₹ 26,255.00 |
76-442 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,255.00
GST (18%): ₹ 4,725.90
Total Price: ₹ 30,980.90
Chemical Name or Material
(S)-1-(Methylsulfonyl)-N-[4-(methylthio)-1-oxo-1-[[4-[3-(pyridin-4-yl)phenyl]thiazol-2-yl]amino]butan-2-yl]-1H-pyrrole-3-carboxamide
Quantity
2 mg
Molecular Formula
C25H25N5O4S3
CAS
2368903-18-6
Target
Bromodomain Inhibitors
Purity
0.95
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / FHT-1015 / 5mg / 719836058 / HY-144896 / / 2368903-18-6 / [null] / 555.690 / C25H25N5O4S3 | eMolecules | ₹ 39,302.40 | |
 | 2368903-18-6 | FHT-1015 | A2B Chem | ₹ 6,853.00 - ₹ 1,19,972.00 |
Related Products
Description
- FHT 1015 is a potent and selective allosteric inhibitor of SMARCA4/SMARCA2 ATPase (also known as BRG1/BRM respectively) of the BAF (BRG/Brahma-associated factors) complex, with IC50s of ≤ 10 nM
- Exhibits selectivity for SMARCA4/SMARCA2 over related CHD4 (IC50 of > 400 μM)
- Mutations in I1143 on SMARCA4 and I1173 on SMARCA2 render these proteins resistant to inhibition by FHT 1015
- The compound induces lineage-specific changes in chromatin accessibility in different cancer cell lines, preventing binding of cancer-associated transcription factors, SOX10 and MITF transcription factors.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: (S)-1-(Methylsulfonyl)-N-[4-(methylthio)-1-oxo-1-[[4-[3-(pyridin-4-yl)phenyl]thiazol-2-yl]amino]butan-2-yl]-1H-pyrrole-3-carboxamide
Quantity: 2 mg
Molecular Formula: C25H25N5O4S3
CAS: 2368903-18-6
Target: Bromodomain Inhibitors
Purity: 0.95
Chemical Name or Material:
(S)-1-(Methylsulfonyl)-N-[4-(methylthio)-1-oxo-1-[[4-[3-(pyridin-4-yl)phenyl]thiazol-2-yl]amino]butan-2-yl]-1H-pyrrole-3-carboxamide
Quantity:
2 mg
Molecular Formula:
C25H25N5O4S3
CAS:
2368903-18-6
Target:
Bromodomain Inhibitors
Purity:
0.95
Chemical Name or Material: __
Quantity: 1 kit
Molecular Formula: __
CAS: __
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1 kit
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Chemical Name or Material: N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity: 10 mg
Molecular Formula: C17H17F2N5O3S
CAS: 1286770-55-5
Target: Secretase Inhibitors
Purity: 0.98
Chemical Name or Material:
N-[3-[(5 R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2 H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Quantity:
10 mg
Molecular Formula:
C17H17F2N5O3S
CAS:
1286770-55-5
Target:
Secretase Inhibitors
Purity:
0.98