78-455-0

Tocris Bioscience™ AZ1 USP25/28 inhibitor

Manufacturer: Fischer Scientific

CAS Number: 2165322-94-9

Select a Size

Pack Size SKU Availability Price
Each of 1 78-455-0-Each-of-1 In Stock ₹ 61,218.18

78-455-0 - Each of 1

₹ 61,218.18

In Stock

Quantity

1

Base Price: ₹ 61,218.18

GST (18%): ₹ 11,019.272

Total Price: ₹ 72,237.452

Chemical Name or Material

2-[[[5-Bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]ethanol

Quantity

50 mg

Molecular Formula

C17H16BrF4NO2

CAS

2165322-94-9

Target

USP28

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
200007275
Tocris Bioscience™ AZ1 USP25/28 inhibitor
Fischer Scientific --
78-451-0
Tocris Bioscience™ AZ1 USP25/28 inhibitor
Fischer Scientific ₹ 14,553.76
50-246-3090
eMolecules​ Medchem Express / USP25/28 inhibitor AZ1 / 5mg / 495799959 / HY-117370 / / 2165322-94-9 / [null] / 422.218 / C17H16BrF4NO2
eMolecules​ ₹ 10,075.55
50-196-9468
Medchemexpress LLC HY-117370 5mg Medchemexpress, USP25/28 inhibitor AZ1 CAS:2165322-94-9 Purity:>98%
Medchemexpress LLC ₹ 7,187.04
BF09618
2165322-94-9 | 2-((5-Bromo-2-((4-fluoro-3-(trifluoromethyl)benzyl)oxy)benzyl)amino)ethan-1-ol
A2B Chem ₹ 6,160.32 - ₹ 33,539.52

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Description

  • AZ1 USP25/28 inhibitor is a selective inhibitor of USP28 (IC50 = 0.6 μM, Kd= 0.2 - 3.7 μM) and USP25 (IC50 = 0.7 μM)
  • AZ1 USP25/28 inhibitor exhibits selectivity for USP25 and USP28 over other DUB family members
  • The compound dose-dependently reduces c-Myc levels in colon carcinoma cells in vitro and induces cell death (EC50 values are 18 - 20 μM)
  • In a mouse Alzheimer's disease model, AZ1 USP25/28 inhibitor reduces amyloid burden, attenuates microglial activation and improves synaptic and cognitive function.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
2-[[[5-Bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]ethanol

Quantity:
50 mg

Molecular Formula:
C17H16BrF4NO2

CAS:
2165322-94-9

Target:
USP28

Purity:
0.98

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Chemical Name or Material:
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Chemical Name or Material:
8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Quantity:
10 mg

Molecular Formula:
C25H21N5O.2HCl

CAS:
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Target:
Akt (Protein Kinase B) Inhibitors

Purity:
0.98