80-535
Tocris Bioscience™ STING Degrader SP23
Manufacturer: Tocris Bioscience™
CAS Number: 2762552-74-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 80-535-Each-of-1 | In Stock | ₹ 31,058.28 |
80-535 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,058.28
GST (18%): ₹ 5,590.49
Total Price: ₹ 36,648.77
Chemical Name or Material
(2E)-N1-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Quantity
5 mg
Molecular Formula
C34H33N7O10
CAS
2762552-74-7
Target
Active Degraders
Purity
98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / PROTAC STING Degrader-1 / 1mg / 742367759 / HY-150608 / / 2762552-74-7 / [null] / 699.677 / C34H33N7O10 | eMolecules | ₹ 27,707.75 | |
 | 2762552-74-7 | PROTAC STING DEGRADER-1 | A2B Chem | ₹ 29,175.96 |
Related Products
Description
- STING Degrader SP23 is a selective stimulator of interferon gene (STING) Degrader (PROTAC™; DC50 = 3.2 μM)
- Comprises the STING inhibitor (C-170), joined by a linker to a CRBN ligand Pomalidomide (Cat
- No
- 6302)
- It does not degrade JAK2, STAT3, PI3K, AKT and TLR4 in THP-1 cells
- STING Degrader SP23 dose dependently reduces the levels of IFN-β, IL-6, and CXCL10 triggered by cGAMP in THP-1 cells; it also modulates the downstream signals of the STING signaling pathway in vivo
- STING Degrader SP23 has high anti-inflammatory efficacy in a cisplatin-induced acute kidney injury mouse model
- Negative control STING Degrader N-Me-SP23 (Cat
- No
- 8054) also available
- PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (2E)-N1-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Quantity: 5 mg
Molecular Formula: C34H33N7O10
CAS: 2762552-74-7
Target: Active Degraders
Purity: 98%
Chemical Name or Material:
(2E)-N1-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Quantity:
5 mg
Molecular Formula:
C34H33N7O10
CAS:
2762552-74-7
Target:
Active Degraders
Purity:
98%
Chemical Name or Material: (2E)-N1-[6-[[2,3-Dihydro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Quantity: 5 mg
Molecular Formula: C35H35N7O10
CAS: 2767427-87-0
Target: Active Degrader Negative Controls
Purity: 98%
Chemical Name or Material:
(2E)-N1-[6-[[2,3-Dihydro-2-(1-methyl-2,6-dioxo-3-piperidinyl)-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Quantity:
5 mg
Molecular Formula:
C35H35N7O10
CAS:
2767427-87-0
Target:
Active Degrader Negative Controls
Purity:
98%
Chemical Name or Material: (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide
Quantity: 10 mg
Molecular Formula: C24H29N3O2
CAS: 658084-64-1
Target: NAMPT Inhibitors
Purity: 98%
Chemical Name or Material:
(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide
Quantity:
10 mg
Molecular Formula:
C24H29N3O2
CAS:
658084-64-1
Target:
NAMPT Inhibitors
Purity:
98%
Chemical Name or Material: Pesticide Calibration Standard
Quantity: 1 mL
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
Pesticide Calibration Standard
Quantity:
1 mL
Molecular Formula:
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CAS:
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Target:
__
Purity:
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