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D2141

6-Diazo-5-oxo-L-norleucine

Name: 6-Diazo-5-oxo-L-norleucine | Sigma Aldrich | Chemikart
Brand: Chemikart
Price: 6679.03 inr
Availability: InStock

>95% (TLC), suitable for ligand binding assays

Manufacturer: Sigma Aldrich

CAS Number: 157-03-9

Synonym(S): (S)-2-Amino-6-diazo-5-oxocaproic acid, DON

Select a Size

Pack Size	SKU	Availability	Price
5 MG	D2141-5-MG	In Stock	₹ 6,679.03
25 MG	D2141-25-MG	In Stock	₹ 20,426.78

D2141 - 5 MG

₹ 6,679.03

In Stock

Quantity

Base Price: ₹ 6,679.03

GST (18%): ₹ 1,202.225

Total Price: ₹ 7,881.255

Assay

>95% (TLC)

Quality Level

200

form

crystalline

technique(s)

ligand binding assay: suitable

color

light yellow

mp

145 °C

antibiotic activity spectrum

neoplastics

Mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O

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Description

General description: Chemical structure: amino acid derivatives
Application: 6-Diazo-5-oxo-L-norleucine (DON) has been used as an inhibitor of glutamine synthetase–glutamine(amide)-2-oxoglutarate aminotransferase.[1]
Biochem/physiol Actions: 6-Diazo-5-oxo-L-norleucine (DON), a glutamine analogue, is used as an inhibitor to study the function, specificity and characteristics of cytidine triphosphate synthase 1(s) (CTPS1) and various glutaminase(s). DON is used to inhibit glutamine (GLN) flux between cells.

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H301 + H311 + H331

Precautionary Statements

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sigma Aldrich

D2141

>95% (TLC), suitable for ligand bin...

Assay:

>95% (TLC)

Quality Level:

200

form:

crystalline

technique(s):

ligand binding assay: suitable

color:

light yellow

mp:

145 °C

antibiotic activity spectrum:

neoplastics

Mode of action:

enzyme | inhibits

storage temp.:

−20°C

SMILES string:

N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O

Sigma Aldrich

D214752

99%...

Assay:

99%

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200

form:

liquid

technique(s):

color:

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

SMILES string:

CCCNCCC

Sigma Aldrich

D215554

99%, mixture of isomers...

Assay:

99%

Quality Level:

200

form:

liquid

technique(s):

color:

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

SMILES string:

CC(O)COCC(C)O.CC(O)COC(C)CO.CC(CO)OC(C)CO

Sigma Aldrich

D2162

≥97% (HPLC)...

Assay:

≥97% (HPLC)

Quality Level:

200

form:

powder

technique(s):

color:

white

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

−20°C

SMILES string:

__

6-Diazo-5-oxo-L-norleucine

Select a Size

Select a Size

Properties

Assay

Quality Level

form

technique(s)

color

mp

antibiotic activity spectrum

Mode of action

storage temp.

SMILES string

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Description

SAFETY INFORMATION

Pictograms

Signal Word

Hazard Statements

Precautionary Statements

Hazard Classifications

WGK

Flash Point(F)

Flash Point(C)

Personal Protective Equipment

Compare Similar Items

Show Difference

Sigma Aldrich

Assay: >95% (TLC) Quality Level: 200 form: crystalline technique(s): ligand binding assay: suitable color: light yellow mp: 145 °C antibiotic activity spectrum: neoplastics Mode of action: enzyme | inhibits storage temp.: −20°C SMILES string: N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O

Sigma Aldrich

Assay: 99% Quality Level: 200 form: liquid technique(s): __ color: __ mp: __ antibiotic activity spectrum: __ Mode of action: __ storage temp.: __ SMILES string: CCCNCCC

Sigma Aldrich

Assay: 99% Quality Level: 200 form: liquid technique(s): __ color: __ mp: __ antibiotic activity spectrum: __ Mode of action: __ storage temp.: __ SMILES string: CC(O)COCC(C)O.CC(O)COC(C)CO.CC(CO)OC(C)CO

Sigma Aldrich

Assay: ≥97% (HPLC) Quality Level: 200 form: powder technique(s): __ color: white mp: __ antibiotic activity spectrum: __ Mode of action: __ storage temp.: −20°C SMILES string: __

Assay:

>95% (TLC)

Quality Level:

200

form:

crystalline

technique(s):

ligand binding assay: suitable

color:

light yellow

mp:

145 °C

antibiotic activity spectrum:

neoplastics

Mode of action:

enzyme | inhibits

storage temp.:

−20°C

SMILES string:

N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O

Assay:

99%

Quality Level:

200

form:

liquid

technique(s):

color:

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

SMILES string:

CCCNCCC

Assay:

99%

Quality Level:

200

form:

liquid

technique(s):

color:

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

SMILES string:

CC(O)COCC(C)O.CC(O)COC(C)CO.CC(CO)OC(C)CO

Assay:

≥97% (HPLC)

Quality Level:

200

form:

powder

technique(s):

color:

white

mp:

antibiotic activity spectrum:

Mode of action:

storage temp.:

−20°C

SMILES string:

__