K1637

Kanamycin sulfate from Streptomyces kanamyceticus

meets USP testing specifications, powder

Manufacturer: Sigma Aldrich

CAS Number: 25389-94-0

Synonym(S): Kanamycin A, Kanamycin sulfate salt

Select a Size

Pack Size SKU Availability Price
1 G K1637-1-G In Stock ₹ 5,412.50
5 G K1637-5-G In Stock ₹ 22,764.98
25 G K1637-25-G In Stock ₹ 72,982.15

K1637 - 1 G

₹ 5,412.50

In Stock

Quantity

1

Base Price: ₹ 5,412.50

GST (18%): ₹ 974.25

Total Price: ₹ 6,386.75

biological source

Streptomyces kanamyceticus

Quality Level

200

Agency

USP/NFmeets USP testing specifications

form

powder

potency

≥750 μg per mg

solubility

H2O: 10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteriamycobacteriamycoplasma

application(s)

pharmaceutical (small molecule)

Mode of action

protein synthesis | interferes

SMILES string

OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

Other Options

Image Product Name Manufacturer Price Range
PHR1487
Kanamycin Sulfate
Supelco ₹ 10,760.05
1355006
Kanamycin sulfate
Sigma Aldrich ₹ 40,756.13
BP861
Kanamycin monosulfate
Sigma Aldrich ₹ 24,789.25
K1377
Kanamycin sulfate from Streptomyces kanamyceticus
Sigma Aldrich ₹ 5,618.18 - ₹ 61,561.78
K0254
Kanamycin solution from Streptomyces kanamyceticus
Sigma Aldrich ₹ 8,475.98
K0129
Kanamycin solution from Streptomyces kanamyceticus
Sigma Aldrich ₹ 2,652.13
K4000
Kanamycin sulfate from Streptomyces kanamyceticus
Sigma Aldrich ₹ 5,022.80 - ₹ 1,02,328.73

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Description

  • General description: Kanamycin Sulfate is a broad spectrum aminoglycoside-antibiotic purified from the bacterium Streptomyces kanamyceticus. Kanamycin Sulfate is a selection agent for cells in culture media and acts by binding to the 30S subunit of the bacterial ribosome which inhibits protein synthesis in susceptible bacteria.
  • Application: Kanamycin sulfate is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100 μg/mL. Kanamycin sulfate from Streptomyces kanamyceticus has been used: in the research of cell type-specific expression of genes[1][2]
  • Biochem/physiol Actions: Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding. Mode of Resistance:Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.Antimicrobial spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
  • Features and Benefits: High quality antibiotic suitable for mulitple research applicationsmeets USP testing specifications
  • Preparation Note: Kanamycin sulfate is soluble in water at 50 mg/mL, yielding a clear solution. It is practically insoluble in alcohol, acetone, chloroform, ether and ethyl acetate. A 1% solution in water has a pH of 6.5 to 8.5. Sterile solutions can be prepared by a sterile filtration, through a .2μm filter.Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at 2-8°C for long term storage.
  • Storage and Stability: Tightly closed. Dry. Keep in a well -ventilated place. Keep locked up or in an area accessible
  • Other Notes: For additional information on our range of Biochemicals, please complete this form.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360D

Precautionary Statements

P201 - P308 + P313

Hazard Classifications

Repr. 1B

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K1637

meets USP testing specifications, p...


biological source:
Streptomyces kanamyceticus

Quality Level:
200

Agency:
USP/NFmeets USP testing specifications

form:
powder

potency:
≥750 μg per mg

solubility:
H2O: 10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycobacteriamycoplasma

application(s):
pharmaceutical (small molecule)

Mode of action:
protein synthesis | interferes

SMILES string:
OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

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