K4000

Kanamycin sulfate from Streptomyces kanamyceticus

Animal Component-free

Manufacturer: Sigma Aldrich

CAS Number: 25389-94-0

Synonym(S): Kanamycin A, Kanamycin sulfate salt

Select a Size

Pack Size SKU Availability Price
1 G K4000-1-G In Stock ₹ 5,022.80
5 G K4000-5-G In Stock ₹ 13,109.08
25 G K4000-25-G In Stock ₹ 57,340.03
50 G K4000-50-G In Stock ₹ 1,02,328.73

K4000 - 1 G

₹ 5,022.80

In Stock

Quantity

1

Base Price: ₹ 5,022.80

GST (18%): ₹ 904.104

Total Price: ₹ 5,926.904

biological source

Streptomyces kanamyceticus

Quality Level

200

form

powder

potency

≥750 μg per mg (dry basis)

color

white to off-white

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteriamycobacteriamycoplasma

Mode of action

protein synthesis | interferes

SMILES string

OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

Other Options

Image Product Name Manufacturer Price Range
55051G
Tocris Bioscience™ Kanamycin Sulfate
Tocris Bioscience™ --
50-255-1784
TOKU-E Kanamycin Sulfate USP, 25389-94-0, 5 g
TOKU-E ₹ 5,732.52
50-255-1781
TOKU-E Kanamycin ReadyMade™ Solution, 25389-94-0, 100 ML
TOKU-E ₹ 5,219.16
11-101-3738
Kanamycin Sulfate Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 12,543.10
50-186-5595
Sigma Aldrich Fine Chemicals Biosciences Kanamycin sulfate United States Pharmacopeia (USP) Reference Standard | 25389-94-0 | 200mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 45,791.71
PHR1487
Kanamycin Sulfate
Supelco ₹ 10,760.05
1355006
Kanamycin sulfate
Sigma Aldrich ₹ 40,756.13
BP861
Kanamycin monosulfate
Sigma Aldrich ₹ 24,789.25
K1377
Kanamycin sulfate from Streptomyces kanamyceticus
Sigma Aldrich ₹ 5,618.18 - ₹ 61,561.78
K0254
Kanamycin solution from Streptomyces kanamyceticus
Sigma Aldrich ₹ 8,475.98

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Description

  • General description: Kanamycin Sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus.
  • Application: Kanamycin sulfate is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100 μg/mL. Kanamycin sulfate from Streptomyces kanamyceticus has been used:in the research of bacterial antibiotic resistance[1][2]in the research on the effect of different antibiotics on bud regeneration[3]
  • Biochem/physiol Actions: Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding. Mode of Resistance:Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.Antimicrobial spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
  • Features and Benefits: High quality antibiotic suitable for mulitple research applications
  • Preparation Note: Kanamycin sulfate is soluble in water at 50 mg/mL, yielding a clear solution. It is practically insoluble in alcohol, acetone, chloroform, ether and ethyl acetate. A 1% solution in water has a pH of 6.5 to 8.5. Sterile solutions can be prepared by a sterile filtration, through a .2μm filter.Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at 2-8°C for long term storage.
  • Storage and Stability: Tightly closed. Dry. Keep in a well -ventilated place. Keep locked up or in an area accessible
  • Other Notes: For additional information on our range of Biochemicals, please complete this form.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360D

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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biological source:
Streptomyces kanamyceticus

Quality Level:
200

form:
powder

potency:
≥750 μg per mg (dry basis)

color:
white to off-white

solubility:
H2O: 50 mg/mL, clear, colorless to faintly yellow

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycobacteriamycoplasma

Mode of action:
protein synthesis | interferes

SMILES string:
OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI:
1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

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CCC(=O)C(O)=O

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1S/C4H6O3/c1-2-3(5)4(6)7/h2H2,1H3,(H,6,7)