N1876

Neomycin trisulfate salt hydrate

powder

Manufacturer: Sigma Aldrich

CAS Number: 1405-10-3

Synonym(S): Framycetin sulfate

Select a Size

Pack Size SKU Availability Price
25 G N1876-25-G In Stock ₹ 5,401.68
100 G N1876-100-G In Stock ₹ 14,722.00

N1876 - 25 G

₹ 5,401.68

In Stock

Quantity

1

Base Price: ₹ 5,401.68

GST (18%): ₹ 972.302

Total Price: ₹ 6,373.982

form

powder

Quality Level

200

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

protein synthesis | interferes

SMILES string

O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O

InChI

1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1

InChI key

WHAGUNPVKDUVFV-QGTTWHFQSA-N

Other Options

Image Product Name Manufacturer Price Range
50-255-1774
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 25 g
TOKU-E ₹ 4,894.03
50-255-1775
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 100 g
TOKU-E ₹ 9,240.48
50-255-1773
TOKU-E Neomycin Sulfate, USP, 1405-10-3, 500 g
TOKU-E ₹ 39,956.52
50-186-3458
Sigma Aldrich Fine Chemicals Biosciences Neomycin sulphate European Pharmacopoeia (EP) Reference Standard | 1405-10-3 |
Sigma Aldrich Fine Chemicals Biosciences ₹ 23,582.90
50-200-8921
Enzo Life Sciences Neomycin . sulfate (25g). CAS: 1405-10-3
Enzo Life Sciences ₹ 44,474.09
1458009
Neomycin sulfate
Sigma Aldrich ₹ 47,987.23
N0401000
Neomycin sulfate, for microbiological assay
Sigma Aldrich ₹ 16,107.60
33492
Neomycin trisulfate salt hydrate
Supelco ₹ 2,673.78
N3144
Neomycin trisulfate salt hydrate
Sigma Aldrich ₹ 28,274.90
N6386
Neomycin trisulfate salt hydrate
Sigma Aldrich ₹ 3,734.63 - ₹ 23,230.45

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells that have been transformed using the selectable marker gene (neo), and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins.[1][2][3].
  • Biochem/physiol Actions: Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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N1876

powder...


form:
powder

Quality Level:
200

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteria

Mode of action:
protein synthesis | interferes

SMILES string:
O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)C(N)[C@@H](O)[C@@H]1O

InChI:
1S/C23H46N6O13.3H2O4S.H2O/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4;/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4);1H2/t5-,6+,7-,8+,9-,10-,11?,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;;/m1..../s1

InChI key:
WHAGUNPVKDUVFV-QGTTWHFQSA-N

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COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc3O2

InChI:
1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-7,10,17,19,21-31,33-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1

InChI key:
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InChI:
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CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12

InChI:
1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1

InChI key:
VWPOSFSPZNDTMJ-UCWKZMIHSA-N