4530970

Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Manufacturer: Fischer Scientific

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Cleavable

No

PEGylated

No

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Description

  • Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm
  • Highlights: Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation “Fix” protein interactions to allow identification of weak or transient protein interactions Protein crosslinking to create bioconjugates via single-step reactions Crosslink oriented antibodies to Protein A or G agarose Immobilize proteins onto amine-coated surfaces

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