Thermo Scientific™ Pierce™ Iodination Beads

Description

• Thermo Scientific™ Pierce Iodination Beads are 3mm diameter polystyrene beads that are coated with an oxidizing reagent, which provides efficient activation of iodine-125 for protein or peptide iodination procedures
• Highlights: Derivatized, uniform, nonporous polystyrene beads Radioiodide incorporation as high as 99%; labeled protein recovery >90% Functions over a broad pH and temperature range Fast and easy to use: iodinations complete in 2 to 15 minutes Reaction stopped by simply removing beads from reaction mixture with tweezers or pasteur pipet; no reducing agent necessary to terminate reaction Additional Features: Iodinates in the presence of azides, detergents, urea and high salt Allows efficient iodination of cell membrane surface proteins More gentle method for iodination than soluble chloramine-T because there is no contact between the protein and the immobilized oxidizing agent 1 Highly reproducible iodinations Can be used to quantitatively iodinate histidine at pH 8.22