BDB550911

BD Annexin V: FITC Fluorescence Microscopy Kit

Manufacturer: BD

The price for this product is unavailable. Please request a quote

For Use With (Application)

Fluorescence Microscopy

Quantity

25 Slides

Product Type

Fluorescence Microscopy Kit

Includes

Annexin V-FITC, Annexin V binding buffer, and PBS buffer

Content And Storage

4°C

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Description

  • Early in apoptosis, before the loss of membrane integrity,phosphatidylserine (PS) translocates from the inner to outer leaflet of plasma membrane, exposing it to external cellular environment at surface of plasma membrane
  • Annexin V is 35-36kDa, calcium-dependent, phospholipid-binding protein with a high affinity for PS and is used to indirectly monitor PS translocation
  • Annexin V assay is facilitated by the observation that PS translocation appears to be a universal apoptotic phenomenon
  • Binds to negatively charged phospholipid surfaces Defined calcium and salt concentrations are required Used in Fluorescence microscopy

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