PRG7102

Promega ADCC Bioassay Effector Cells, Propagation Model

Manufacturer: Promega

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Pack Size SKU Availability Price
Each of 1 PRG7102-Each-of-1 In Stock ₹ 80,85,591.12

PRG7102 - Each of 1

₹ 80,85,591.12

In Stock

Quantity

1

Base Price: ₹ 80,85,591.12

GST (18%): ₹ 14,55,406.402

Total Price: ₹ 95,40,997.522

Quantity

2 x 1.0 mL

Content And Storage

Store below -140°C (freezer or liquid nitrogen vapor phase)

For Use With (Application)

Allows Propagation and Banking of the ADCC Bioassay, V Variant, Effector Cells

Product Type

ADCC Bioassay Effector Cells (CPM)

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Description

  • Fc receptor-mediated antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of action (MOA) by which antibodies target disease cells for elimination
  • Classic methods used to measure ADCC utilize primary donor peripheral blood mononuclear cells (PBMCs) or purified natural killer (NK) cells that express Fc receptors on their cell surface
  • Following engagement with the Fc region of a relevant antibody bound to a target disease cell, Fc receptors transduce intracellular signals within the effector cell resulting in elimination of the target cell
  • These primary cell-based assays are highly variable as a result of donor differences and the requirement for cell culture and expansion.

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2 x 1.0 mL

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Store below -140°C (freezer or liquid nitrogen vapor phase)

For Use With (Application):
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ADCC Bioassay Effector Cells (CPM)

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