PV4748
Invitrogen™ LanthaScreen™ TR-FRET BACE1 Assay Kit
Manufacturer: Invitrogen™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PV4748-Each-of-1 | In Stock | ₹ 1,51,612.32 |
PV4748 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,51,612.32
GST (18%): ₹ 27,290.218
Total Price: ₹ 1,78,902.538
Content And Storage
Store in freezer (-5°C to -30°C).
Product Line
LanthaScreen™
Substrate Type
Beta Secretase Substrate
Quantity
800 x 20 μL Assays
Target
Beta Secretase (BACE1)
Assay
β-Secretase Assay
Substrate Properties
Peptide-Based Substrate
For Use With (Application)
TR-FRET
Shipping Condition
Dry Ice
Related Products
Description
- BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases, early-onset familial AD can be attributed to a 'Swedish' mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that focus on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase
- Invitrogen's LanthaScreen™ TR-FRET BACE1 assay provides sensitive high-throughput screening for potential inhibitors of beta-secretase
- The kit uses a terbium (Tb)-labeled anti-biotin antibody and a fluorescein-labeled BACE1-biotin substrate in a homogeneous TR-FRET assay format (Figure 1)
- Contents and Storage: The LanthaScreen™ TR-FRET BACE1 Assay Kit contains BACE1 protein, fluorescently labeled BACE1 substrate, Tb-labeled anti-biotin antibody, and buffers
- Store components as indicated in the assay protocol (-80°C, -20°C, or +4°C).
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Content And Storage: Store in freezer (-5°C to -30°C).
Product Line: LanthaScreen™
Substrate Type: Beta Secretase Substrate
Quantity: 800 x 20 μL Assays
Target: Beta Secretase (BACE1)
Assay: β-Secretase Assay
Substrate Properties: Peptide-Based Substrate
For Use With (Application): TR-FRET
Shipping Condition: Dry Ice
Content And Storage:
Store in freezer (-5°C to -30°C).
Product Line:
LanthaScreen™
Substrate Type:
Beta Secretase Substrate
Quantity:
800 x 20 μL Assays
Target:
Beta Secretase (BACE1)
Assay:
β-Secretase Assay
Substrate Properties:
Peptide-Based Substrate
For Use With (Application):
TR-FRET
Shipping Condition:
Dry Ice
Content And Storage: Terbium-labeled p4E-BP1 (pThr46) antibody in HEPES buffered saline.Store at -20°C.
Product Line: LanthaScreen™
Substrate Type: __
Quantity: 25 μg
Target: __
Assay: __
Substrate Properties: __
For Use With (Application): __
Shipping Condition: Dry Ice
Content And Storage:
Terbium-labeled p4E-BP1 (pThr46) antibody in HEPES buffered saline.Store at -20°C.
Product Line:
LanthaScreen™
Substrate Type:
__
Quantity:
25 μg
Target:
__
Assay:
__
Substrate Properties:
__
For Use With (Application):
__
Shipping Condition:
Dry Ice
Content And Storage: Terbium-labeled p4E-BP1 (pThr46) antibody in HEPES buffered saline.Store at -20°C.
Product Line: LanthaScreen™
Substrate Type: __
Quantity: 1 mg
Target: __
Assay: __
Substrate Properties: __
For Use With (Application): __
Shipping Condition: Dry Ice
Content And Storage:
Terbium-labeled p4E-BP1 (pThr46) antibody in HEPES buffered saline.Store at -20°C.
Product Line:
LanthaScreen™
Substrate Type:
__
Quantity:
1 mg
Target:
__
Assay:
__
Substrate Properties:
__
For Use With (Application):
__
Shipping Condition:
Dry Ice
Content And Storage: Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline.Store at -20°C.
Product Line: LanthaScreen™
Substrate Type: __
Quantity: 25 μg
Target: __
Assay: __
Substrate Properties: __
For Use With (Application): __
Shipping Condition: Dry Ice
Content And Storage:
Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline.Store at -20°C.
Product Line:
LanthaScreen™
Substrate Type:
__
Quantity:
25 μg
Target:
__
Assay:
__
Substrate Properties:
__
For Use With (Application):
__
Shipping Condition:
Dry Ice