11-849-010MG

MilliporeSigma™ Calbiochem™ ATIC Dimerization Inhibitor

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 11-849-010MG-Each-of-1 In Stock ₹ 18,340.64

11-849-010MG - Each of 1

₹ 18,340.64

In Stock

Quantity

1

Base Price: ₹ 18,340.64

GST (18%): ₹ 3,301.315

Total Price: ₹ 21,641.955

Color

White

Target Proteins

ATIC

Solubility

DMSO

Form

Solid

Description

97% by HPLC

Molecular Formula

C21H33N7O5

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (K i = 691 nM, K d = 240nM)
  • AITC is a bifunctional enzyme that catalyzes the last two steps of de novo purine biosynthesis
  • Increases the intracellular levels of AICAR leading to the activation of AMP-activated protein kinase (AMPK)
  • Shown to reduce cell viability in a dose-dependent manner
  • Exhibits a longer half-life and sustained AMPK activation (∽ 24 hours) compared to AICA-riboside (Cat
  • No
  • 123040).

Compare Similar Items

Show Difference

Img

MilliporeSigma™

11-849-010MG

--


Color:
White

Target Proteins:
ATIC

Solubility:
DMSO

Form:
Solid

Description:
97% by HPLC

Molecular Formula:
C21H33N7O5

Content And Storage:
Protect from light

Quantity:
10 mg

Img

Fischer Scientific

11-850-01

--


Color:
__

Target Proteins:
__

Solubility:
__

Form:
__

Description:
__

Molecular Formula:
__

Content And Storage:
__

Quantity:
__

Img

Fischer Scientific

11-850-010MG

--


Color:
White

Target Proteins:
ATM Kinase

Solubility:
DMSO

Form:
Solid

Description:
__

Molecular Formula:
C21H17NO3S2

Content And Storage:
Protect from light

Quantity:
10 mg

Img

Fischer Scientific

11-850-02MG

--


Color:
White

Target Proteins:
ATM Kinase

Solubility:
DMSO

Form:
Solid

Description:
__

Molecular Formula:
C21H17NO3S2

Content And Storage:
Protect from light

Quantity:
2 mg