32-451-95MG

MilliporeSigma™ Calbiochem™ InSolution™ eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

Manufacturer: MilliporeSigma™

CAS Number: 315706-13-9

Select a Size

Pack Size SKU Availability Price
Each of 1 32-451-95MG-Each-of-1 In Stock ₹ 16,024.53

32-451-95MG - Each of 1

₹ 16,024.53

In Stock

Quantity

1

Base Price: ₹ 16,024.53

GST (18%): ₹ 2,884.415

Total Price: ₹ 18,908.945

Formulation

A 25 mM (5mg/443μL) solution of eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

Target Proteins

eIF4E

Molecular Formula

C18H12Cl2N4O4S

Content And Storage

Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light

Quantity

5 mg

Description

95% by HPLC (sum of two isomers)

CAS

315706-13-9

Formula Weight

451.3g/mol

Form

Liquid

Other Options

Image Product Name Manufacturer Price Range
50-226-0239
Medchemexpress LLC HY-19831 10mg , 4EGI-1 CAS:315706-13-9 Purity:>98%
Medchemexpress LLC ₹ 14,194.40
32-451-710MG
MilliporeSigma™ Calbiochem™ eIF4E/eIF4G Interaction Inhibitor, 4EGI-1
MilliporeSigma™ ₹ 25,626.93
50-136-4703
Selleck Chemical LLC 4EGI-1 10mg 315706-13-9
Selleck Chemical LLC ₹ 20,226.38
50-200-9242
Enzo Life Sciences 4EGI-1 (2mg). CAS: 315706-13-9
Enzo Life Sciences ₹ 29,026.23
AD50989
315706-13-9 | eIF4E/eIF4G Interaction Inhibitor, 4EGI-1
A2B Chem ₹ 1,026.72 - ₹ 31,058.28

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Description

  • A cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; K D = 25μM) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex formation
  • Reported to downregulate the protein, but not mRNA, levels of c-Myc and Bcl-x L in Jurkat cells (8 hrs), leading to apoptotic cell death after prolonged exposure (24 hrs, IC 50 ∽25μM)
  • Shown to be brain permeant and reduce neuroligin protein levels, and restore L-LTP threshold and rescue autistic-like behaviours in Eif4ebp2 knockout mice.

Compare Similar Items

Show Difference

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MilliporeSigma™

32-451-95MG

--


Formulation:
A 25 mM (5mg/443μL) solution of eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

Target Proteins:
eIF4E

Molecular Formula:
C18H12Cl2N4O4S

Content And Storage:
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light

Quantity:
5 mg

Description:
95% by HPLC (sum of two isomers)

CAS:
315706-13-9

Formula Weight:
451.3g/mol

Form:
Liquid

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MilliporeSigma™

32-452-125MG

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Formulation:
__

Target Proteins:
__

Molecular Formula:
C27H25Cl2N7O7

Content And Storage:
Protect from light

Quantity:
25 mg

Description:
90% by HPLC

CAS:
412960-54-4

Formula Weight:
630.4g/mol

Form:
Solid

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Invitrogen

32-460-0

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Formulation:
PBS with 0.1% sodium azide; pH 7.4

Target Proteins:
__

Molecular Formula:
__

Content And Storage:
-20°C

Quantity:
100 μg

Description:
__

CAS:
__

Formula Weight:
__

Form:
Liquid

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Fischer Scientific

32-462-21MG

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Formulation:
__

Target Proteins:
Microtubule-stimulated ATPase activity of the mitotic motor

Molecular Formula:
C16H18N2O2S

Content And Storage:
Protect from light

Quantity:
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Description:
__

CAS:
863774-58-7

Formula Weight:
302.4g/mol

Form:
Solid