49-562-45MG

MilliporeSigma™ Calbiochem™ InSolution™ Olomoucine

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 49-562-45MG-Each-of-1 In Stock ₹ 24,042.36

49-562-45MG - Each of 1

₹ 24,042.36

In Stock

Quantity

1

Base Price: ₹ 24,042.36

GST (18%): ₹ 4,327.625

Total Price: ₹ 28,369.985

Formulation

A 50 mM (5mg/336μl) solution of Olomoucine in DMSO.

Target Proteins

p34cdk1/cyclin B

Formula Weight

298.3g/mol

Form

Liquid

Description

98% by HPLC

Molecular Formula

C15H18N6O

Content And Storage

Hygroscopic, Protect from light

Quantity

5 mg

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Description

  • A purine derivative that acts as a potent and selective inhibitor of p34cdc2/cyclin B (IC 50 = 7μM) and related kinases, including p33cdk2/cyclin A (IC 50 = 7μM), p33cdk2/cyclin E (IC 50 = 7μM), p33cdk5/p35 (IC 50 = 3μM), and p44MAPK (IC 50 = 25μM)
  • Acts by competing for the ATP binding domain of the kinase
  • Exhibits reduced sensitivity towards related kinases, p34cdk4/cyclin D1 (IC 50 >1 mM) and p40cdk6/cyclin D3 (IC 50 >250μM)
  • Does not significantly affect the activity of other protein kinases even at 1mm concentrations
  • Known to inhibit DNA synthesis in interleukin-2 stimulated T lymphocytes and triggers G 1 arrest similar to that observed in interleukin-2 deprived cells
  • Also used to synchronize cells in G 1 .

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MilliporeSigma™

49-562-45MG

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Formulation:
A 50 mM (5mg/336μl) solution of Olomoucine in DMSO.

Target Proteins:
p34cdk1/cyclin B

Formula Weight:
298.3g/mol

Form:
Liquid

Description:
98% by HPLC

Molecular Formula:
C15H18N6O

Content And Storage:
Hygroscopic, Protect from light

Quantity:
5 mg

Img

Fischer Scientific

49-581-0

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Formulation:
__

Target Proteins:
__

Formula Weight:
386.42

Form:
__

Description:
__

Molecular Formula:
C19H21FN2O2.0.5C4H4O4

Content And Storage:
__

Quantity:
10 mg

Img

Fischer Scientific

49-585-0

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Formulation:
__

Target Proteins:
__

Formula Weight:
386.42

Form:
__

Description:
__

Molecular Formula:
C19H21FN2O2.0.5C4H4O4

Content And Storage:
__

Quantity:
50 mg

Img

Fischer Scientific

49-592-5

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Formulation:
__

Target Proteins:
__

Formula Weight:
Observed MW: 425.44

Form:
__

Description:
__

Molecular Formula:
C25H19N3O4

Content And Storage:
__

Quantity:
25 mg