65-841-15MG
MilliporeSigma™ Calbiochem™ InSolution™ AG490
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 65-841-15MG-Each-of-1 | In Stock | ₹ 8,005.85 |
65-841-15MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 8,005.85
GST (18%): ₹ 1,441.053
Total Price: ₹ 9,446.903
Formulation
A 100 mM (5mg/170μl) solution of AG490 in DMSO.
Molecular Formula
C17H14N2O3
Content And Storage
Hygroscopic, Protect from light
Quantity
5 mg
Description
98% by HPLC
Formula Weight
294.3g/mol
Form
Liquid
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Description
- Potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC 50 = 100nM)
- Jak family tyrosine kinase inhibitor
- Inhibition of Jak2 by AG 490 selectively blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death, with no harmful effect on normal haematopoiesis
- Inhibits the constitutive activation of STAT-3 and IL-2-induced growth of MF tumor cells
- AG 490 has also been shown to inhibit the autokinase activity of JAK3
- Also reported to inhibit guanylyl cyclase.
Compare Similar Items
Show Difference
Formulation: A 100 mM (5mg/170μl) solution of AG490 in DMSO.
Molecular Formula: C17H14N2O3
Content And Storage: Hygroscopic, Protect from light
Quantity: 5 mg
Description: 98% by HPLC
Formula Weight: 294.3g/mol
Form: Liquid
Formulation:
A 100 mM (5mg/170μl) solution of AG490 in DMSO.
Molecular Formula:
C17H14N2O3
Content And Storage:
Hygroscopic, Protect from light
Quantity:
5 mg
Description:
98% by HPLC
Formula Weight:
294.3g/mol
Form:
Liquid
Formulation: __
Molecular Formula: C18H22N2O
Content And Storage: Protect from light
Quantity: 5 mg
Description: 99% by TLC
Formula Weight: 282.4g/mol
Form: Solid
Formulation:
__
Molecular Formula:
C18H22N2O
Content And Storage:
Protect from light
Quantity:
5 mg
Description:
99% by TLC
Formula Weight:
282.4g/mol
Form:
Solid
Formulation: __
Molecular Formula: C10H5N3O3
Content And Storage: Protect from light
Quantity: 5 mg
Description: 95% by HPLC
Formula Weight: 215.2g/mol
Form: Solid
Formulation:
__
Molecular Formula:
C10H5N3O3
Content And Storage:
Protect from light
Quantity:
5 mg
Description:
95% by HPLC
Formula Weight:
215.2g/mol
Form:
Solid
Formulation: __
Molecular Formula: C6H12N4O2.HCl
Content And Storage: __
Quantity: 10 mg
Description: __
Formula Weight: 208.65
Form: __
Formulation:
__
Molecular Formula:
C6H12N4O2.HCl
Content And Storage:
__
Quantity:
10 mg
Description:
__
Formula Weight:
208.65
Form:
__