50-471-20001

MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor VI, ICG-001

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-471-20001-Each-of-1 In Stock ₹ 26,049.60

50-471-20001 - Each of 1

₹ 26,049.60

In Stock

Quantity

1

Base Price: ₹ 26,049.60

GST (18%): ₹ 4,688.928

Total Price: ₹ 30,738.528

Color

Off-white

Target Proteins

CREB-binding protein

Solubility

DMSO

Form

Powder

Description

99% by HPLC

Molecular Formula

C33H32N4O4

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable pyrazinopyrimidinecarboxamide that competes against β-catenin for CBP (CREB-binding protein) binding and selectively prevents CBP- but not p300-, dependent TCF/β-catenin transcriptional regulations both in cultures in vitro (5 to 25μM) and in mice in vivo (5mg/kg/day via osmotic pump infusion), while not affecting CBP-dependent transcriptional activities mediated by the AP-1 or CRE complex
  • Shown to reactivate p300//TCF/β-catenin-mediated neuronal differentiation upon NGF stimulation in PS-1 L286V mutant-expressing PC-12 cultures and be efficacious in alleviating bleomycin- (0,08 units/50μL/mouse; administered intranasally; Cat
  • No
  • 203401) induced pulmonary fibrosis in mice.

Compare Similar Items

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Img

MilliporeSigma™

50-471-20001

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Color:
Off-white

Target Proteins:
CREB-binding protein

Solubility:
DMSO

Form:
Powder

Description:
99% by HPLC

Molecular Formula:
C33H32N4O4

Content And Storage:
Protect from light

Quantity:
10 mg

Img

MilliporeSigma™

50-471-30001

--


Color:
White

Target Proteins:
mGlu1 receptors

Solubility:
DMSO

Form:
Powder

Description:
98% by HPLC

Molecular Formula:
C13H13NO4

Content And Storage:
Protect from light

Quantity:
5 mg

Img

MilliporeSigma™

50-474-40001

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Color:
__

Target Proteins:
DNA polymerase α and δ

Solubility:
__

Form:
Liquid

Description:
98% by TLC

Molecular Formula:
C20H34O4

Content And Storage:
Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light

Quantity:
1 mg

Img

MilliporeSigma™

50-474-50001

--


Color:
White

Target Proteins:
mGlu7 receptors

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC

Molecular Formula:
C28H28N2·2HCl

Content And Storage:
Protect from light

Quantity:
10 mg