50-547-90001
MilliporeSigma™ Calbiochem™ SIRT1/2/3 pan Inhibitor
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-547-90001-Each-of-1 | In Stock | ₹ 25,577.71 |
50-547-90001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,577.71
GST (18%): ₹ 4,603.988
Total Price: ₹ 30,181.698
Color
Pale Yellow
Target Proteins
SIRT1/2/3
Solubility
DMSO
Form
Powder
Description
97% by HPLC
Molecular Formula
C19H27N5O2S
Content And Storage
Protect from light
Quantity
10 mg
Related Products
Description
- A thienopyrimidinylcarboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC 50 = 15, 10, and 33nM for SIRT1, 2, and 3, respectively)
- Shown to bind to the SIRT catalytic site and occupy both the nicotinamide C-pocket and acetyl lysine substrate channel
- Exhibits high selectivity over a panel of protein kinases, nuclelar receptors, GPCRs, and ion-channels (IC 50 > 10μM)
- Poorly affects hERG and cytochrome P450s (> 50μM)
- Exhibits desirable stability in microsomal preparations (human CL int = 15.8μL/min/mg, mouse CL int = 12.7μL/min/mg) and high solubility (297μM), and low LogD (2.73).
Compare Similar Items
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Color: Pale Yellow
Target Proteins: SIRT1/2/3
Solubility: DMSO
Form: Powder
Description: 97% by HPLC
Molecular Formula: C19H27N5O2S
Content And Storage: Protect from light
Quantity: 10 mg
Color:
Pale Yellow
Target Proteins:
SIRT1/2/3
Solubility:
DMSO
Form:
Powder
Description:
97% by HPLC
Molecular Formula:
C19H27N5O2S
Content And Storage:
Protect from light
Quantity:
10 mg
Color: __
Target Proteins: __
Solubility: __
Form: __
Description: __
Molecular Formula: __
Content And Storage: __
Quantity: __
Color:
__
Target Proteins:
__
Solubility:
__
Form:
__
Description:
__
Molecular Formula:
__
Content And Storage:
__
Quantity:
__
Color: __
Target Proteins: __
Solubility: __
Form: Liquid
Description: __
Molecular Formula: __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Quantity: 25 μg
Color:
__
Target Proteins:
__
Solubility:
__
Form:
Liquid
Description:
__
Molecular Formula:
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Quantity:
25 μg
Color: __
Target Proteins: __
Solubility: __
Form: Liquid
Description: __
Molecular Formula: __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Quantity: 100 μg
Color:
__
Target Proteins:
__
Solubility:
__
Form:
Liquid
Description:
__
Molecular Formula:
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Quantity:
100 μg