52-123-31MG

MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor IV

Manufacturer: MilliporeSigma™

CAS Number: 627518-40-5

Select a Size

Pack Size SKU Availability Price
Each of 1 52-123-31MG-Each-of-1 In Stock ₹ 22,793.18

52-123-31MG - Each of 1

₹ 22,793.18

In Stock

Quantity

1

Base Price: ₹ 22,793.18

GST (18%): ₹ 4,102.772

Total Price: ₹ 26,895.952

Color

Off-white

Target Proteins

PDGFR Tyrosine Kinase

Molecular Formula

C18H16FN3O2

Solubility

DMSO or MeOH

Form

Solid

Description

98% by HPLC

CAS

627518-40-5

Formula Weight

325.3g/mol

Content And Storage

Protect from light

Quantity

1 mg

Other Options

Image Product Name Manufacturer Price Range
7199111
Tocris™ JNJ 10198409
Fischer Scientific --
69-761-0
Tocris™ JNJ 10198409
Fischer Scientific ₹ 27,789.89
69-765-0
Tocris™ JNJ 10198409
Fischer Scientific ₹ 1,16,022.78
50-154-266
Biotang Inc JNJ-10198409, Free Base, > 99%, 25MG, CAS#627518-40-5, M.W.325.34, PDGF Receptor Tyrosine Kinase Inhibitor IV; RWJ-540973. RS323-25MG
Biotang Inc ₹ 80,193.68
50-186-7702
Sigma Aldrich Fine Chemicals Biosciences JNJ-10198409 >=98% (HPLC), solid | 627518-40-5 | 1MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 25,888.74
AB74978
627518-40-5 | N-(3-Fluorophenyl)-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
A2B Chem ₹ 2,224.56 - ₹ 11,293.92

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Description

  • A cell-permeable indenopyrazole compound that displays potent antiproliferative properties in several human tumor cell lines (IC 50 < 33nM)
  • Shown to act as an ATP-competitive and reversible inhibitor of PDGFR (IC 50 = 4.2nM and 45nM for -β and -α, respectively) and c-Abl (IC 50 = 22nM)
  • Exhibits less activity towards Lck, c-Src, and Fyn (IC 50 = 100 nM, 185nM and 378 nM, respectively) and exhibits little or no inhibition toward VEGFR, HER-2, Cdk's-1,-2,-4 &-7, bFGFR-1 and EGFR (IC 50 = 3.1μM, > 10μM, > 10μM, 45.8μM and > 100μM, respectively).

Compare Similar Items

Show Difference

Img

MilliporeSigma™

52-123-31MG

--


Color:
Off-white

Target Proteins:
PDGFR Tyrosine Kinase

Molecular Formula:
C18H16FN3O2

Solubility:
DMSO or MeOH

Form:
Solid

Description:
98% by HPLC

CAS:
627518-40-5

Formula Weight:
325.3g/mol

Content And Storage:
Protect from light

Quantity:
1 mg

Img

MilliporeSigma™

52-127-55MG

--


Color:
Yellow

Target Proteins:
Both PDK1 and Akt activities

Molecular Formula:
C10H4N6O

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC (sum of two isomers)

CAS:
331253-86-2

Formula Weight:
224.2g/mol

Content And Storage:
Protect from light

Quantity:
5 mg

Img

Fischer Scientific

52-141-0

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Color:
__

Target Proteins:
__

Molecular Formula:
__

Solubility:
__

Form:
__

Description:
__

CAS:
__

Formula Weight:
__

Content And Storage:
__

Quantity:
10 mg

Img

Fischer Scientific

52-145-0

--


Color:
__

Target Proteins:
__

Molecular Formula:
__

Solubility:
__

Form:
__

Description:
__

CAS:
__

Formula Weight:
__

Content And Storage:
__

Quantity:
50 mg