53-155-20001

MilliporeSigma™ Calbiochem™ Argonaute-2 Inhibitor, BCI-137

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 53-155-20001-Each-of-1 In Stock ₹ 24,589.09

53-155-20001 - Each of 1

₹ 24,589.09

In Stock

Quantity

1

Base Price: ₹ 24,589.09

GST (18%): ₹ 4,426.036

Total Price: ₹ 29,015.126

Color

Gray-white

Target Proteins

Argonaute-2

Solubility

DMSO

Form

Solid

Description

97% by HPLC

Molecular Formula

C11H11N3O6S

Content And Storage

Protect from light

Quantity

25 mg

Related Products

Img

MilliporeSigma™

50-630-40001

--

Img

MilliporeSigma™

50-589-60001

--

Img

MilliporeSigma™

53-064-80001

--

Img

MilliporeSigma™

50-050-10001

--

Img

MilliporeSigma™

50-459-90001

--

Img

MilliporeSigma™

53-170-90001

--

Img

MilliporeSigma™

50-529-90001

--

Img

MilliporeSigma™

53-137-10001

--

Description

  • A cell-permeable, non-toxic dioxotetrahydroquinoxaline compound that mimics uridine and directly and reversibly interacts with the microRNA (miRNA) binding domain of Argonaute-2 (Ago2; K D = 126μM) and significantly inhibits binding of miR-20a, miR-26a, miR-107, miR-223, and let-7a to Ago2
  • However, it does not affect Ago2 stability in cells
  • Displaces Ago2 from the miR-155 host gene promoter region (70% reduction in Ago2 association) and increases histone H4 acetylation (∽300%) in NB4 leukemia cell line
  • Promotes retinoic acid-induced differentiation of NB4 cells to granulocytes
  • Please note that the molecular weight for this compound is batch-specific due to variable water content.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

53-155-20001

--


Color:
Gray-white

Target Proteins:
Argonaute-2

Solubility:
DMSO

Form:
Solid

Description:
97% by HPLC

Molecular Formula:
C11H11N3O6S

Content And Storage:
Protect from light

Quantity:
25 mg

Img

Fischer Scientific

53-157-941

--


Color:
__

Target Proteins:
__

Solubility:
__

Form:
Liquid

Description:
__

Molecular Formula:
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Quantity:
25 Tests

Img

Fischer Scientific

53-157-942

--


Color:
__

Target Proteins:
__

Solubility:
__

Form:
Liquid

Description:
__

Molecular Formula:
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Quantity:
100 Tests

Img

MilliporeSigma™

53-162-00001

--


Color:
White

Target Proteins:
APT1

Solubility:
DMSO

Form:
Solid

Description:
98% by HPLC

Molecular Formula:
C18H17ClF3N3O3

Content And Storage:
Protect from light

Quantity:
10 mg