55-736-05MG
MilliporeSigma™ Calbiochem™ Roscovitine
Manufacturer: Fischer Scientific
CAS Number: 186692-46-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 55-736-05MG-Each-of-1 | In Stock | ₹ 24,076.58 |
55-736-05MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,076.58
GST (18%): ₹ 4,333.784
Total Price: ₹ 28,410.364
Color
White to Off-white
CAS
186692-46-6
Formula Weight
354.5g/mol
Form
Solid
Purity
95% by HPLC
Target Proteins
p34cdk1/cyclin B
Molecular Formula
C19H26N6O
Solubility
DMSO
Quantity
5 mg
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ Roscovitine | Fischer Scientific | -- | |
| | MilliporeSigma™ Calbiochem™ Roscovitine | Fischer Scientific | ₹ 6,684.80 | |
 | Medchemexpress LLC Seliciclib | 186692-46-6 | MFCD02266401 | 10mg | Medchemexpress LLC | ₹ 7,097.20 | |
 | Sigma Aldrich Fine Chemicals Biosciences Roscovitine >=98% (TLC) | 186692-46-6 | MFCD02266401 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 41,820.02 | |
| | Enzo Life Sciences (R)-Roscovitine (2mg). CAS: 186692-46-6 | Enzo Life Sciences | ₹ 9,347.43 | |
 | Sigma Aldrich Fine Chemicals Biosciences Roscovitine | 186692-46-6 | MFCD02266401 | 1 mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 11,948.45 | |
 | Apexbio Technology LLC potent CDK inhibitor 186692-46-6. MFCD02266401 | Apexbio Technology LLC | ₹ 17,112.00 | |
 | 186692-46-6 | Roscovitine | A2B Chem | ₹ 2,053.44 - ₹ 38,416.44 |
Related Products
Description
- Inhibits p34cdk1/cyclin B (IC50 = 650 nM), p33cdk2/cyclin A (IC50 = 700 nM), p33cdk2/cyclin E (IC50 = 700 nM), and p33cdk5/p35 (IC50 = 200 nM) by competing for the ATP binding domain of the kinases
- Exhibits reduced sensitivity towards related kinases including ERK1 and ERK2 (IC50 = 34μM and 14μM, respectively)
- Roscovitine does not significantly affect the activity of other protein kinases even at 100μM, including p34cdk4/cyclin D1 and p40cdk6/cyclin D2
- Compared to olomoucine, roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle
- A 50mm (5mg/282μl) solution of Roscovitine (Cat
- No
- 557364) in DMSO is also available.
Compare Similar Items
Show Difference
Color: White to Off-white
CAS: 186692-46-6
Formula Weight: 354.5g/mol
Form: Solid
Purity: 95% by HPLC
Target Proteins: p34cdk1/cyclin B
Molecular Formula: C19H26N6O
Solubility: DMSO
Quantity: 5 mg
Color:
White to Off-white
CAS:
186692-46-6
Formula Weight:
354.5g/mol
Form:
Solid
Purity:
95% by HPLC
Target Proteins:
p34cdk1/cyclin B
Molecular Formula:
C19H26N6O
Solubility:
DMSO
Quantity:
5 mg
Color: White
CAS: 186692-45-5
Formula Weight: 354.5g/mol
Form: Solid
Purity: __
Target Proteins: p34cdk1/cyclin B kinase
Molecular Formula: C19H26N6O
Solubility: DMSO
Quantity: 1 mg
Color:
White
CAS:
186692-45-5
Formula Weight:
354.5g/mol
Form:
Solid
Purity:
__
Target Proteins:
p34cdk1/cyclin B kinase
Molecular Formula:
C19H26N6O
Solubility:
DMSO
Quantity:
1 mg
Color: White to Off-white
CAS: 83-79-4
Formula Weight: 394.4g/mol
Form: Solid
Purity: __
Target Proteins: NADH-CoQ reductase
Molecular Formula: C23H22O6
Solubility: CHCl3, DMSO, or EtOH
Quantity: 1 g
Color:
White to Off-white
CAS:
83-79-4
Formula Weight:
394.4g/mol
Form:
Solid
Purity:
__
Target Proteins:
NADH-CoQ reductase
Molecular Formula:
C23H22O6
Solubility:
CHCl3, DMSO, or EtOH
Quantity:
1 g
Color: Orange
CAS: 82-08-6
Formula Weight: 516.5g/mol
Form: Solid
Purity: __
Target Proteins: PKCδ
Molecular Formula: C30H28O8
Solubility: DMSO or EtOH
Quantity: 10 mg
Color:
Orange
CAS:
82-08-6
Formula Weight:
516.5g/mol
Form:
Solid
Purity:
__
Target Proteins:
PKCδ
Molecular Formula:
C30H28O8
Solubility:
DMSO or EtOH
Quantity:
10 mg