65-854-81MG

MilliporeSigma™ Calbiochem™ InSolution™ AG 1478

Manufacturer: MilliporeSigma™

CAS Number: 175178-82-2

Select a Size

Pack Size SKU Availability Price
Each of 1 65-854-81MG-Each-of-1 In Stock ₹ 10,540.14

65-854-81MG - Each of 1

₹ 10,540.14

In Stock

Quantity

1

Base Price: ₹ 10,540.14

GST (18%): ₹ 1,897.225

Total Price: ₹ 12,437.365

Color

Clear to Faint Tan

Description

98% by HPLC

CAS

175178-82-2

Formula Weight

315.8g/mol

Form

Liquid

Formulation

A 10 mM (1mg/317μl) solution of AG 1478 in DMSO.

Target Proteins

Epidermal growth factor receptor kinase

Molecular Formula

C16H14ClN3O2

Content And Storage

Protect from light

Quantity

1 mg

Other Options

Image Product Name Manufacturer Price Range
50-176-1088
Sigma Aldrich Fine Chemicals Biosciences Tyrphostin AG 1478 >=98% | 175178-82-2 | MFCD00270914 | 1MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 8,239.43
50-176-1089
Sigma Aldrich Fine Chemicals Biosciences Tyrphostin AG 1478 | 175178-82-2 | MFCD00270914 | 5 mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 24,525.77
AE98820
175178-82-2 | AG 1478
A2B Chem ₹ 15,914.16

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Description

  • Highly potent and specific inhibitor of the epidermal growth factor (EGF) receptor tyrosine kinase (IC 50 = 3nM)
  • Much higher concentrations are required for inhibition of the kinase activity of the closely related HER2 ( neu/erb -B2) receptor (IC 50 > 100μM), the platelet-derived growth factor (PDGF) receptor (IC 50 > 100μM), and p210 Bcr-Abl (IC 50 >50μM)
  • Its mechanism of inhibition likely mimics that of the related compound, 4-(3-chloroanilino)quinazoline (CAQ), a competitive inhibitor with respect to ATP.

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MilliporeSigma™

65-854-81MG

--


Color:
Clear to Faint Tan

Description:
98% by HPLC

CAS:
175178-82-2

Formula Weight:
315.8g/mol

Form:
Liquid

Formulation:
A 10 mM (1mg/317μl) solution of AG 1478 in DMSO.

Target Proteins:
Epidermal growth factor receptor kinase

Molecular Formula:
C16H14ClN3O2

Content And Storage:
Protect from light

Quantity:
1 mg

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MilliporeSigma™

65-855-05MG

--


Color:
White

Description:
95% by HPLC

CAS:
71897-07-9

Formula Weight:
234.3g/mol

Form:
Solid

Formulation:
__

Target Proteins:
PDGFR kinase

Molecular Formula:
C16H14N2

Content And Storage:
Protect from light

Quantity:
5 mg

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Tocris Bioscience™

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Color:
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Description:
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CAS:
1049722-30-6

Formula Weight:
__

Form:
__

Formulation:
__

Target Proteins:
__

Molecular Formula:
C32H36N10O2

Content And Storage:
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Quantity:
5 mg

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Tocris Bioscience™

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Color:
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Description:
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CAS:
243984-11-4

Formula Weight:
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Form:
__

Formulation:
__

Target Proteins:
__

Molecular Formula:
C15H17ClFNO4S

Content And Storage:
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Quantity:
5 mg