7060062
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
Manufacturer: Fischer Scientific
CAS Number: 4449-51-8
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Color
Off-white
Target Proteins
Hh signaling in Shh-light2 assay
Molecular Formula
C27H41NO2
Solubility
DMSO, EtOH, or DMF
Form
Solid
Description
97% by HPLC
CAS
4449-51-8
Formula Weight
411.6g/mol
Content And Storage
Protect from light
Other Options
Related Products
Description
- A cell-permeable steroidal alkaloid and cholesterol mimic that displays both teratogenic and antitumor activities
- It disrupts cholesterol bio-synthesis and specifically antagonizes shh (Sonic Hedgehog) signaling pathway through direct interaction with Smo (smoothened), a distant relative of G-protein-coupled receptors
- A valuable tool for studying the involvement of shh signaling in the development of various tumors
- Tomatidine (Cat
- No
- 614350) can be used as a negative control
- Also available as a 10mm solution in Ethanol (Cat
- No
- 239806).
Compare Similar Items
Show Difference
Color: Off-white
Target Proteins: Hh signaling in Shh-light2 assay
Molecular Formula: C27H41NO2
Solubility: DMSO, EtOH, or DMF
Form: Solid
Description: 97% by HPLC
CAS: 4449-51-8
Formula Weight: 411.6g/mol
Content And Storage: Protect from light
Color:
Off-white
Target Proteins:
Hh signaling in Shh-light2 assay
Molecular Formula:
C27H41NO2
Solubility:
DMSO, EtOH, or DMF
Form:
Solid
Description:
97% by HPLC
CAS:
4449-51-8
Formula Weight:
411.6g/mol
Content And Storage:
Protect from light
Color: Pale Yellow
Target Proteins: Hh signaling in Shh-light2 assay
Molecular Formula: C44H63N3O4
Solubility: DMSO, EtOH, or MeOH
Form: Solid
Description: 70% by HPLC (sum of two isomers)
CAS: __
Formula Weight: 698g/mol
Content And Storage: Protect from light
Color:
Pale Yellow
Target Proteins:
Hh signaling in Shh-light2 assay
Molecular Formula:
C44H63N3O4
Solubility:
DMSO, EtOH, or MeOH
Form:
Solid
Description:
70% by HPLC (sum of two isomers)
CAS:
__
Formula Weight:
698g/mol
Content And Storage:
Protect from light
Color: Yellow
Target Proteins: DNA-PK
Molecular Formula: C17H17NO3
Solubility: DMSO
Form: Solid
Description: 95% by HPLC
CAS: 404009-46-7
Formula Weight: 283.3g/mol
Content And Storage: Protect from light
Color:
Yellow
Target Proteins:
DNA-PK
Molecular Formula:
C17H17NO3
Solubility:
DMSO
Form:
Solid
Description:
95% by HPLC
CAS:
404009-46-7
Formula Weight:
283.3g/mol
Content And Storage:
Protect from light
Color: White or Off-white
Target Proteins: Fluorogenic caspase-3 substrate.
Molecular Formula: C36H38F3N5O14
Solubility: DMSO
Form: Solid
Description: 95% by HPLC
CAS: __
Formula Weight: 821.7g/mol
Content And Storage: __
Color:
White or Off-white
Target Proteins:
Fluorogenic caspase-3 substrate.
Molecular Formula:
C36H38F3N5O14
Solubility:
DMSO
Form:
Solid
Description:
95% by HPLC
CAS:
__
Formula Weight:
821.7g/mol
Content And Storage:
__