Cyclopamine- KAAD, CAS 306387-90-6, is a cell-permeable potent analog of Cyclopamine (Cat. No. 239803) that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity (IC50= 20 nM).
Manufacturer: Fischer Scientific
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Pale Yellow
Hh signaling in Shh-light2 assay
698g/mol
Protect from light
70% by HPLC (sum of two isomers)
C44H63N3O4
DMSO, EtOH, or MeOH
Solid