7060151

MilliporeSigma™ Calbiochem™ Ru360

A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).

Manufacturer: Fischer Scientific

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Color

Reddish Brown

Target Proteins

Ca2+ uptake into mitochondria in vitro

Formula Weight

550.8g/mol

Content And Storage

Hygroscopic, Protect from light

Description

97% by capillary electrophoresis

Molecular Formula

C2H26Cl3N8O5Ru2

Solubility

deoxygenated H2O

Form

Solid

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Description

  • A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM)
  • Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min)
  • Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.

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Fischer Scientific

7060151

A cell-permeable oxygen-bridged din...


Color:
Reddish Brown

Target Proteins:
Ca2+ uptake into mitochondria in vitro

Formula Weight:
550.8g/mol

Content And Storage:
Hygroscopic, Protect from light

Description:
97% by capillary electrophoresis

Molecular Formula:
C2H26Cl3N8O5Ru2

Solubility:
deoxygenated H2O

Form:
Solid

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Formula Weight:
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Content And Storage:
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Description:
98% by HPLC

Molecular Formula:
C21H16N3OSF

Solubility:
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Target Proteins:
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Formula Weight:
413.9g/mol

Content And Storage:
Hygroscopic, Protect from light

Description:
95% by HPLC

Molecular Formula:
C21H16FN3OS·HCl

Solubility:
DMSO or H2O

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Solubility:
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