7121949
Novus Biologicals™ Pam3CSK4, TLR1 and TLR2 Ligand
Applications:Functional, In vitro assay, In vivo assay, Ligand Activation
Manufacturer: Fischer Scientific
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Concentration
0.5 mg/mL
For Use With (Application)
Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Species
Human/Mouse
Content And Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Target
Pam3CSK4, TLR1 and TLR2 Ligand
Related Products
Description
- Pam3CSK4, TLR1 and TLR2 Ligand is a synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein
- It activates monocytes and macrophages and is also a potent activator of proinflammatory transcription factor NF-kB
- Pam3CSK4, TLR1 and TLR2 Ligand is recognized by a heterodimer formed between TLR1 and TLR2
- Pam3CSK4, TLR1 and TLR2 Ligand stimulation: If your cell line does not naturally express TLR1+ TLR2, co-transfect with plasmids pCMV/TLR1and pCMV/TLR2
- Forty-eight hours after transfection, stimulate cells with 10 to 100ng/ml of Pam3CSK4 for 6 to 24 hours
- Determine Pam3CSK4 stimulation using appropriate detection assays
- Buffer: Sterile water
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Concentration: 0.5 mg/mL
For Use With (Application): Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Species: Human/Mouse
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Target: Pam3CSK4, TLR1 and TLR2 Ligand
Concentration:
0.5 mg/mL
For Use With (Application):
Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Species:
Human/Mouse
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Target:
Pam3CSK4, TLR1 and TLR2 Ligand
Concentration: 0.1 mg/mL
For Use With (Application): __
Species: Human/Mouse/Avian
Content And Storage: Store at -20C. Avoid freeze-thaw cycles.
Target: MALP-2, TLR6 and TLR2 Ligand
Concentration:
0.1 mg/mL
For Use With (Application):
__
Species:
Human/Mouse/Avian
Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.
Target:
MALP-2, TLR6 and TLR2 Ligand
Concentration: __
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