Thermo Scientific™ Sodium Deoxycholate Detergent

Description

• Thermo Scientific™ Sodium Deoxycholate is an ionic detergent that is especially useful for disrupting and dissociating protein interactions
• Sodium deoxycholate (deoxycholic acid) is a water-soluble, bile-acid, ionic detergent commonly used in protein methods
• It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer) but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement
• Highlights: Popular anionic, bile-acid detergent for many laboratory uses Effective in disrupting and dissociating many types of protein interaction Can be removed from solution by dialysis Useful for elution or regeneration of certain kinds of affinity columns High-purity compound with low UV absorptivity Detergent Properties: Alternative Names: Sodium deoxycholic acid; deoxycholate, sodium salt Chemical Name: 3, 12-α-Dihydroxy-5β-cholan-24-oic acid, monosodium salt Molecular Weight: 414.6 Detergent Class: Ionic (anionic) Aggregation Number: 5 (average) Micelle Molecular Weight: 2000 (average) Critical Micelle Concentration (CMC): 2 to 6mM (0.083 to 0.249%, w/v) Cloud Point: Unknown Dialyzable: Yes