Anti-Mouse IgG (Fab specific)–Peroxidase antibody produced in goat

Description

• General description: Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice possess five classes of immunoglobulins- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.
• Immunogen: purified mouse IgG, Fab fragment
• Application: Murine IgG levels were quantitated in brain abscess homogenates by ELISA using HRP conjugated goat anti-mouse Fab specific antibody as the detection antibody.
• Biochem/physiol Actions: Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG2a has cytotropic properties and IgG2 molecules have the ability to activate the complement system. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
• Physical form: Solution in 0.01 M phosphate buffered saline pH 7.4, containing 0.05% MIT
• Preparation Note: Adsorbed with human IgG and rat serum proteins to reduce background staining with human or rat samples.
• Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
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