Anti-Epidermal Growth Factor Receptor/Erb B1 antibody produced in goat

Description

• Immunogen: purified, NSO cell-derived recombinant human epidermal growth factor receptor extracellular domain.
• Application: Anti-Epidermal Growth Factor Receptor/Erb B1 antibody produced in goat was used for immunoblotting to analyze stable expression of anti-EGFR shRNA in MCF10A breast epithelial cell line.
• Biochem/physiol Actions: EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer.
• Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.