HPA008879

Anti-ADAM7 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Manufacturer: Sigma Aldrich

Synonym(S): Anti-ADAM metallopeptidase domain 7, Anti-EAPI, Anti-GP-83

Select a Size

Pack Size SKU Availability Price
100 μL HPA008879-100-μL In Stock ₹ 48,995.40

HPA008879 - 100 μL

₹ 48,995.40

In Stock

Quantity

1

Base Price: ₹ 48,995.40

GST (18%): ₹ 8,819.172

Total Price: ₹ 57,814.572

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

orthogonal RNAseqLearn more about Antibody Enhanced Validation

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Description

  • General description: ADAM7 (A disintegrin and metalloproteinase 7) belongs to the family of zinc-based proteinases, metzincins called ADAM. It is normally not expressed in melanocytes, but is expressed in melanoma cells. It is composed of the “Met turn” and three conserved histidine residues. Its cytoplasmic region contains an Src homology region 3 (SH3)-binding domain and a phosphorylation site. This gene is localized to human chromosome 8p12. In mice, this protein is expressed in the caput region of the epididymis and in the anterior pituitary gonadotropes.
  • Immunogen: ADAM metallopeptidase domain 7 recombinant protein epitope signature tag (PrEST)
  • Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
  • Biochem/physiol Actions: ADAM7 (A disintegrin and metalloproteinase 7) is one of the most frequently mutated ADAM family member, and is mutated in more than 12% melanoma cases. It does not have protease activity, but is thought to be involved in protein folding and protein-protein interactions.
  • Features and Benefits: Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways:IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.Protein array of 364 human recombinant protein fragments.
  • Linkage: Corresponding Antigen APREST70777
  • Physical form: Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.
  • Legal Information: Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
  • Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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buffered aqueous glycerol solution

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