HPA011227

Anti-MSN antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Manufacturer: Sigma Aldrich

Synonym(S): Anti-Membrane-organizing extension spike protein, Anti-Moesin

Select a Size

Pack Size SKU Availability Price
100 μL HPA011227-100-μL In Stock ₹ 48,995.40

HPA011227 - 100 μL

₹ 48,995.40

In Stock

Quantity

1

Base Price: ₹ 48,995.40

GST (18%): ₹ 8,819.172

Total Price: ₹ 57,814.572

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

rat, human, mouse

enhanced validation

independentorthogonal RNAseqLearn more about Antibody Enhanced Validation

Related Products

Img

Sigma Aldrich

HPA019006

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA021257

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA017342

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA018537

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA009128

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA016739

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA020549

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA012010

Prestige Antibodies® Powered by Atl...

Description

  • General description: MSN (moesin) is a member of the ERM (ezrin, radixin and moesin) family of proteins. This family consists of three members, which have a FERM domain in the N-terminal, an α-helical linker region of ~200 amino acids, and a C-terminal of ~70 amino acids. MSN has a molecular weight of 80kDa.
  • Immunogen: Moesin recombinant protein epitope signature tag (PrEST)
  • Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
  • Biochem/physiol Actions: MSN (moesin) is an intracellular protein which plays a role in cell adhesion, formation of microtubules and ruffling of cell membrane. It connects the cell membrane to cytoskeleton. In mononuclear phagocytes, it regulates lipopolysaccharide (LPS)-mediated events. Studies suggest that MSN might be involved in innate immune response as well as periodontal diseases by regulating TLR4-dependent pattern recognition. Its expression is disrupted in various cancers, and is associated with poor prognosis. It is also overexpressed in metastatic breast cancer cells. It might aid in the metastasis of fluid-borne tumors, by facilitating extravasation of these tumor cells, through polarization of cortex. MSN is a marker of adenomyosis, and is up-regulated in the same. It might be involved in endometrium being extended into the myometrium. It is overexpressed in astrocytomas, which is linked to poor prognosis. It might be involved in the formation and progression of astrocytomas.
  • Features and Benefits: Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways:IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.Protein array of 364 human recombinant protein fragments.
  • Linkage: Corresponding Antigen APREST72484
  • Physical form: Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
  • Legal Information: Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Compare Similar Items

Show Difference

Img

Sigma Aldrich

HPA011227

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
rat, human, mouse

enhanced validation:
independentorthogonal RNAseqLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA011249

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
human

enhanced validation:
orthogonal RNAseqLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA011268

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
human

enhanced validation:
orthogonal RNAseqLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA011271

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
mouse, rat, human

enhanced validation:
orthogonal RNAseqindependentRNAi knockdownLearn more about Antibody Enhanced Validation