Monoclonal Anti-Human IgG2 antibody produced in mouse

Description

• General description: Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Human IgG consists of four subclasses.
• Specificity: The antibody is specific for human IgG2 and is non-reactive with other IgG subclasses. This clone has been singled out as the most widely applicable IgG2 specific monoclonal antibody by the IUIS/WHO study.
• Application: Monoclonal Anti-Human IgG2 antibody has been used in in enzyme linked immunosorbent assay (ELISA) and in western blotting.It may also be used:in imprint immunofixationin immunofluorometric assayin hemagglutinationin hemagglutination inhibitionin particle counting immunoassayin detection of cytoplasmic IgG
• Biochem/physiol Actions: Anti-polysaccharide responses are mainly of the IgG2 sub-class while protein antigens give rise to IgG1 and IgG3 antibodies. Lipopolysaccharides stimulate an IgG2 response in peripheral blood leukocytes (PBL′s).
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