MAB2627

Anti-VCAM-1 (CD106) Antibody, clone 6C7.1

clone 6C7.1, from rat

Manufacturer: Sigma Aldrich

Synonym(S): vascular cell adhesion molecule 1, vascular cell adhesion protein 1, CD106 antigen

Select a Size

Pack Size SKU Availability Price
100 μG MAB2627-100-μG In Stock ₹ 43,730.00

MAB2627 - 100 μG

₹ 43,730.00

In Stock

Quantity

1

Base Price: ₹ 43,730.00

GST (18%): ₹ 7,871.40

Total Price: ₹ 51,601.40

biological source

rat

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6C7.1, monoclonal

species reactivity

mouse

technique(s)

flow cytometry: suitableimmunocytochemistry: suitableimmunohistochemistry: suitableimmunoprecipitation (IP): suitable

isotype

IgG1κ

NCBI accession no.

NP_035823

UniProt accession no.

P29533

Description

  • General description: Vascular cell adhesion protein 1 (VCAM-1) is a cell surface adhesion molecule belonging to the immunoglobulin cell-cell adhesion receptor family and is comprised of seven Ig-like C2-type domains. VCAM-1 is a crucial component in cell-cell recognition and seems to be involved in cellular adhesion between endothelial cells and leukocytes. It has a regulatory role for both signal transduction and adhesion through its interaction with leukocyte beta-1 integrin VLA4, an interaction that is potentially involved in immune and inflammatory emigration responses of leukocytes. Studies have shown upregulation of VCAM-1 to be critical in responding to inflammatory diseases such as atherosclerosis. VCAM-1 is primarily expressed in endothelial cells and is expressed as two known isoforms found within the cell membrane. Isoform 1 functions as a single-pass type 1 membrane protein, while Isoform 2 acts as a GPI-anchor.
  • Immunogen: Mouse endothelial cells
  • Application: Anti-VCAM-1 (CD106) Antibody, clone 6C7.1 is an antibody against VCAM-1 (CD106) for use in FC, IP, IC, IH.
  • Quality: Evaluated by Flow Cytometry in mouse bone marrow cells.Flow Cytometry Analysis: 10 µg of this antibody detected VCAM-1 on mouse bone marrow cells.
  • Target description: 81 kDa calculated
  • Physical form: Format: Purified
  • Other Notes: Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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rat

Quality Level:
100

antibody form:
purified immunoglobulin

antibody product type:
primary antibodies

clone:
6C7.1, monoclonal

species reactivity:
mouse

technique(s):
flow cytometry: suitableimmunocytochemistry: suitableimmunohistochemistry: suitableimmunoprecipitation (IP): suitable

isotype:
IgG1κ

NCBI accession no.:
NP_035823

UniProt accession no.:
P29533

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