Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5

Description

• General description: Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.
• Specificity: Glial fibrillar acidic protein. On western blots of extracts from a human glioma cell line (U33CG/343MG), MAB360 recognizes a band at approximately 51 kDa corresponding to GFAP (Debus, 1983). By immunohistochemistry it recognizes astrocytes and Bergmann glia cells, glioma and glial cell derived tumors. Shows no cross-reactivity with vimentin.
• Immunogen: Purified GFAP from porcine spinal cord.
• Application: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5 detects level of Glial Fibrillary Acidic Protein & has been published & validated for use in IC, IH, IH(P) & WB with more than 65 product citations.
• Quality: Routinely evaluated by Western Blot on Mouse brain lysates.Western Blot Analysis: 1:1000 dilution of this lot detected GFAP on 10 μg of Mouse brain lysates.
• Target description: ~ 51 kDa
• Linkage: Replaces: 04-1031; 04-1062
• Physical form: Unpurified mouse monoclonal IgG1 liquid in buffer containing 15 mM sodium azide.
• Analysis Note: ControlPositive Control: Cultured astrocytes, brain tissue (white matter), spinal chord, retina
• Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
• Legal Information: CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany