Anti-Mucin-9 Antibody, clone 7E10

Description

• General description: Oviduct-specific glycoprotein (UniProt: Q12889; also known as Estrogen-dependent oviduct protein, Mucin-9, Muc-9, Oviductal glycoprotein, Oviductin) is encoded by the OVGP1 (also known as MUC9, OGP) gene (Gene ID: 5016) in human. The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats. Mucin-9 belongs to the glycosyl hydrolase 18 family that plays a key role in sperm capacitation, fertilization, and development of early embryos. It is secreted from non-ciliated oviductal epithelial cells and its expression is highest at the time of ovulation. Mucin-9 is synthesized with a 21 amino acid signal peptide that is subsequently cleaved off to generate mature protein. Mucin-9 is an estrogen-dependent protein that is secreted into the lumen of the oviduct and associates with the zona pellucida of postovulatory oocytes in oviductal transit, but is absent in ovarian oocytes.
• Specificity: Clone 7E10 detects Mucin-9 (Oviductin) in human oviduct sections.
• Immunogen: A mixture of GST-tagged recombinant fragments corresponding to 81 amino acids from the N-terminal half and 112 amino acids from the C-terminal region of human Mucin-9/Oviductin.
• Application: Anti-Mucin-9, clone 7E10, Cat. No. MABC1109, is mouse monoclonal antibody that detects Mucin-9 (Oviductin) and has been tested for use in ELISA, Immunohistochemistry (Paraffin), and Western Blotting.
• Quality: Evaluated by Immunohistochemistry in human oviduct tissue.Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Mucin-9 in human oviduct tissue.
• Target description: 75.42 kDa calculated.
• Physical form: Format: Purified
• Storage and Stability: Stable for 1 year at 2-8°C from date of receipt.
• Other Notes: Concentration: Please refer to lot specific datasheet.
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.