Anti-Chicken IgY (IgG) (H+L), highly cross-adsorbed, CF™405M antibody produced in goat

Description

• General description: Immunoglobulin Y is an antibody produced in birds. IgY is similar to mammalian IgG but differs in some characteristics from IgG. IgY does not bind with mammalian complements nor rheumatoid factor, which are present in mammalian serum and anti-mammalian IgG antibodies. During oogenesis in chicken, IgY can pass across the follicular epithelium of the ovary and aggregate in the yolk. The heavy chain of IgY and mammalian IgG has a molecular weight of 68kDa and 50kDa, respectively. The structure of mammalian IgG is considered more stable than that of IgY. IgG antibodies, which often cross-react to IgG from different mammalian species, exhibit low cross-reactivity to IgY. Thus, IgY is beneficial when it is used as a biochemical/clinical reagent.
• Specificity: Binds all chicken IgYs (minimal cross-reaction with bovine, goat, guinea pig, syrian hamster, horse, human, mouse, rabbit, rat and sheep proteins)
• Immunogen: chicken IgY (H+L)
• Application: Anti-Chicken IgY (IgG) (H+L), highly cross-adsorbed, CF™405M antibody produced in goat has been used in immunohistochemistry.
• Features and Benefits: Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
• Physical form: Supplied in phosphate buffered saline with 0.05% sodium azide, 50% glycerol and 0.2% BSA.
• Preparation Note: Protect from light. The antibody solution should be gently mixed before use.
• Legal Information: This product is distributed by Sigma-Aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyer′s own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
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