EZRMFGF21
Rat/Mouse FGF-21 ELISA Kit
measures and quantifies FGF-21 levels in 10 µl - 20 µl serum, plasma or cell culture supernatent
Manufacturer: Millipore
Synonym(S): Fibroblast growth factor 21
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 96 WELLS | EZRMFGF21-96-WELLS | In Stock | ₹ 98,720.00 |
EZRMFGF21 - 96 WELLS
In Stock
Quantity
1
Base Price: ₹ 98,720.00
GST (18%): ₹ 17,769.60
Total Price: ₹ 1,16,489.60
product name
Rat / Mouse FGF-21 ELISA Kit, This Rat / Mouse FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
Quality Level
200
species reactivity
mouse, rat
packaging
kit of 1 × 96 wells
parameter
10—20 μL sample volume (4hr assay)
assay range
standard curve range: 50-12000 pg/mLinter-assay cv: <8%intra-assay cv: <10%
technique(s)
ELISA: suitable
input
sample type cell culture supernatantsample type serumsample type plasma (K2 EDTA)
application(s)
research use
detection method
colorimetric (450nm/590nm)
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Description
- General description: Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. No significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.Although considerable progress has been made in the understanding of the pathobiology of type 2 diabetes, as well in the development of new compounds for the treatment of diabetic patients, this disease remains a major global health concern. Consequently, Millipore is pleased to offer the Rat/Mouse FGF-21 ELISA kit for the quantification of FGF-21 in rat and mouse serum and plasma samples. The insulin-independent activities of FGF-21, as well as the absence of the weight gain effects of insulin, thiazolidinediones and other anti-diabetic drugs, distinguish it from current insulin-sensitizing drugs, making it a promising therapeutic.
- Specificity: Cross-reactivity to Human FGF-21: 39% No significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
- Application: Research CategoryMetabolism
- Other Notes: Please contact Technical Service for linearity of dilution.
- Disclaimer: For research use only. Not for use in diagnostic procedures.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
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Quality Level: 200
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parameter: 10—20 μL sample volume (4hr assay)
assay range: standard curve range: 50-12000 pg/mLinter-assay cv: <8%intra-assay cv: <10%
technique(s): ELISA: suitable
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product name:
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Quality Level:
200
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mouse, rat
packaging:
kit of 1 × 96 wells
parameter:
10—20 μL sample volume (4hr assay)
assay range:
standard curve range: 50-12000 pg/mLinter-assay cv: <8%intra-assay cv: <10%
technique(s):
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sample type cell culture supernatantsample type serumsample type plasma (K2 EDTA)
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