RAB0024

Human β-2 Microglobulin ELISA Kit

for serum, plasma, cell culture supernatant and urine

Manufacturer: Sigma Aldrich

Synonym(S): B2M

Select a Size

Pack Size SKU Availability Price
1 KIT RAB0024-1-KIT In Stock ₹ 64,524.30

RAB0024 - 1 KIT

₹ 64,524.30

In Stock

Quantity

1

Base Price: ₹ 64,524.30

GST (18%): ₹ 11,614.374

Total Price: ₹ 76,138.674

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitablecapture ELISA: suitable

input

sample type cell culture supernatant(s)sample type plasmasample type serumsample type urine

assay range

inter-assay cv: <12%intra-assay cv: <10%sensitivity: 6 pg/mLstandard curve range: 15.6-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... B2M(567)

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Description

  • General description: β2-microglobulin (B2M) is a non-glycosylated polypeptide composed of 99 amino acids. It is present on the surface of all nucleated cells.[1] The protein is characterized with a single polypeptide chain, which is linked noncovalently to major histocompatibility complex (MHC) class I cell surface antigen.[2] The gene coding for B2M is mapped to human chromosome 15q.[3]
  • Immunogen: Recombinant Human β-2-Microglobulin
  • Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
  • Biochem/physiol Actions: β2-microglobulin (B2M) plays a vital role in cell survival, proliferation and metastasis in various types of cancer. Elevated concentration of β-2-microglobulin (B2M) can be considered as a prognostic marker for hemophagocytic lymphohistiocytosis (HLH).[2] Elevated concentration of circulating B2M, due to renal dysfunction and long term hemodialysis, leads to dialysis-related amyloidosis.[4] Overexpression of serum B2M is observed in hepatitis C virus (HCV) related chronic liver diseases, therefore it might act as a potential marker for the HCV disease progression towards cirrhosis and carcinoma.[1] Missense mutation in the B2M gene results in familial hypercatabolic hypoproteinemia (FHH).[5]
  • Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

WGK

WGK 3

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RAB0024

for serum, plasma, cell culture sup...


species reactivity:
human

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type cell culture supernatant(s)sample type plasmasample type serumsample type urine

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 6 pg/mLstandard curve range: 15.6-1000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... B2M(567)

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human

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kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type plasmasample type serumsample type urinesample type cell culture supernatant(s)

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 40 pg/mLstandard curve range: 40.96-10000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... BCAM(4059)

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assay range:
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colorimetric

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wet ice

storage temp.:
−20°C

Gene Information:
human ... BIRC3(330)