RAB0484
Human Osteoprotegerin / TNFRSF11b ELISA Kit
for serum, plasma, cell culture supernatant and urine
Manufacturer: Sigma Aldrich
Synonym(S): OPG
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | RAB0484-1-KIT | In Stock | ₹ 66,133.80 |
RAB0484 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 66,133.80
GST (18%): ₹ 11,904.084
Total Price: ₹ 78,037.884
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitablecapture ELISA: suitable
input
sample type serumsample type urinesample type cell culture supernatant(s)sample type plasma
assay range
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 1 pg/mLstandard curve range: 1.23-900 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TNFRSF11B(4982)
Related Products
Description
- General description: The Human Osteoprotegerin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Osteoprotegerin in serum, plasma, cell culture supernatants and urine.Osteoprotegerin (OPG) is encoded by the gene mapped to human chromosome 8q24.[1] It is a member of the TNFR (tumor necrosis factor receptor) superfamily that can act as a decoy receptor for RANKL (receptor activator of nuclear factor kappa-B ligand) and TRAIL (tumor necrosis factor-related apoptosis-inducing ligand).[2][3] OPG is expressed in a wide variety of tissues, including adult heart, lung, kidney and liver. It is secreted both as a monomeric and a dimeric protein.[4]
- Immunogen: Recombinant Human OPG
- Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
- Biochem/physiol Actions: Binding of soluble osteoprotegerin (OPG) to sRANKL (soluble receptor activator of nuclear factor κ-B ligand) inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells. This process leads to excess accumulation of bone and cartilage.[3] Changes in the level of serum OPG are associated with atherosclerosis and cardiovascular disorders(CVDs).[2] It might also be associated with malignancy and plays a regulatory role in multiple myeloma, prostate, breast, bladder and gastric carcinoma.[5] OPG plays a vital role in bone metabolism and is involved in inhibition of ovariectomy-associated bone loss in rats.[4][5] It is also used as a potent biomarker for CVD.[1]
- Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
WGK
WGK 3
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species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type serumsample type urinesample type cell culture supernatant(s)sample type plasma
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 1 pg/mLstandard curve range: 1.23-900 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... TNFRSF11B(4982)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type serumsample type urinesample type cell culture supernatant(s)sample type plasma
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 1 pg/mLstandard curve range: 1.23-900 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... TNFRSF11B(4982)
species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type cell culture supernatant(s)sample type serumsample type plasma
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 30 pg/mLstandard curve range: 32.77-8000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... TNFRSF14(8764)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type cell culture supernatant(s)sample type serumsample type plasma
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 30 pg/mLstandard curve range: 32.77-8000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... TNFRSF14(8764)
species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type urinesample type plasmasample type serumsample type cell culture supernatant(s)
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 15 pg/mLstandard curve range: 13.7-10000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... TNFRSF18(8784)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type urinesample type plasmasample type serumsample type cell culture supernatant(s)
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 15 pg/mLstandard curve range: 13.7-10000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... TNFRSF18(8784)
species reactivity: human
packaging: kit of 96 wells (12 strips x 8 wells)
technique(s): ELISA: suitablecapture ELISA: suitable
input: sample type tissue lysatesample type cell lysate
assay range: inter-assay cv: <12%intra-assay cv: <10%sensitivity: 15 pg/mLstandard curve range: 13.7-10000 pg/mL
detection method: colorimetric
shipped in: wet ice
storage temp.: −20°C
Gene Information: human ... TNFRSF18(8784)
species reactivity:
human
packaging:
kit of 96 wells (12 strips x 8 wells)
technique(s):
ELISA: suitablecapture ELISA: suitable
input:
sample type tissue lysatesample type cell lysate
assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 15 pg/mLstandard curve range: 13.7-10000 pg/mL
detection method:
colorimetric
shipped in:
wet ice
storage temp.:
−20°C
Gene Information:
human ... TNFRSF18(8784)