P1951

Phalloidin Peptide

≥90% (HPLC), solid, TRITC labeled

Manufacturer: Sigma Aldrich

Synonym(S): Phalloidin-TRITC

Select a Size

Pack Size SKU Availability Price
0.1 MG P1951-0.1-MG In Stock ₹ 38,915.88

P1951 - 0.1 MG

₹ 38,915.88

In Stock

Quantity

1

Base Price: ₹ 38,915.88

GST (18%): ₹ 7,004.858

Total Price: ₹ 45,920.738

product name

Phalloidin–Tetramethylrhodamine B isothiocyanate, sequence from Amanita phalloides(synthetic: peptide sequence)

biological source

sequence from Amanita phalloides (synthetic: peptide sequence)

Quality Level

200

form

solid

fluorescence

λex 540-545 nm; λem 570-573 nm

storage temp.

−20°C

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Description

  • General description: Phalloidin is a phallotoxin produced by death cap mushroom Amanita phalloides. It is a cyclic peptide, which interacts with actin, and this was first identified in phalloidin-poisoned rats. It is a heptapeptide, cyclic in nature, with a crosslink between tryptophan at position 6 and cysteine at position 3.[1] The side chain of amino acid 7 (γ-δ-dihydroxyleucine) in phalloidin, is accessible to modifications, through which florescent labelled phalloidin compounds can be produced.[2]
  • Application: Fluorescent phallotoxin which may be used to identify filamentous actin.Phalloidin-Tetramethylrhodamine B isothiocyanate has been used:-In Immunofluorescence for staining Filamentous actin (F-actin)[3]To stain cells during immunocytochemical and cytochemical analysis[4]To label actin microfilaments for fluorescence microscopy[5]
  • Biochem/physiol Actions: Phalloidin interacts with polymeric actin, and not oligomeric or monomeric forms. This interaction leads to highly stabilized actin filaments, which resist depolymerization and disassembly. In rats, this toxin causes death due to liver hemorrhage, and cells show abnormal actin clustering.[1] The affinity of phalloidin to actin is not significantly altered after derivatizing florescent labelled phalloidin compounds. These compounds can be used to study actin structure and organization within eukaryotic cells.[2]
  • Other Notes: May contain mixed isomers

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330

Precautionary Statements

P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Phalloidin–Tetramethylrhodamine B isothiocyanate, sequence from Amanita phalloides(synthetic: peptide sequence)

biological source:
sequence from Amanita phalloides (synthetic: peptide sequence)

Quality Level:
200

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solid

fluorescence:
λex 540-545 nm; λem 570-573 nm

storage temp.:
−20°C

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