C9742
Clarithromycin
≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 81103-11-9
Synonym(S): 6-O-methyl erythromycin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | C9742-100-MG | In Stock | ₹ 10,998.20 |
| 250 MG | C9742-250-MG | In Stock | ₹ 16,064.30 |
| 1 G | C9742-1-G | In Stock | ₹ 48,052.18 |
C9742 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 10,998.20
GST (18%): ₹ 1,979.676
Total Price: ₹ 12,977.876
Quality Level
200
Assay
≥95% (HPLC)
form
powder
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
Mode of action
protein synthesis | interferes
SMILES string
O[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
InChI
1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key
AGOYDEPGAOXOCK-KCBOHYOISA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Clarithromycin | Supelco | ₹ 11,506.98 | |
| | Clarithromycin | Sigma Aldrich | ₹ 16,107.60 | |
| | Clarithromycin | Sigma Aldrich | ₹ 40,756.13 | |
| | Clarithromycin Identity | Sigma Aldrich | ₹ 1,29,412.88 | |
| | Clarithromycin for peak identification | Sigma Aldrich | ₹ 16,107.60 | |
| | Clarithromycin | Sigma Aldrich | ₹ 9,785.80 |
Related Products
Description
- General description: Chemical structure: macrolide
- Application: Clarithromycin is a semisynthetic macrolide antibiotic that is derived from erythromycin. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration . Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression[1]. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD)[2]. It is used to study bacterial protein synthesis and peptide translation.
- Biochem/physiol Actions: Clarithromycin inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin is first metabolized to 14-OH clarithromycin, which is active and works synergistically with its parent compound. Clarithromycin penetrates the bacteria cell wall and reversibly binds to domain V of the 23S ribosomal RNA of the 50S subunit of the bacterial ribosome, blocking translocation of aminoacyl transfer-RNA and polypeptide synthesis. Clarithromycin also inhibits the hepatic microsomal CYP3A4 isoenzyme and P-glycoprotein, an energy-dependent drug efflux pump.
- Preparation Note: Practically insoluble in water, soluble in acetone and methylene chloride, slightly soluble in methanol.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 200
Assay: ≥95% (HPLC)
form: powder
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteria
Mode of action: protein synthesis | interferes
SMILES string: O[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
InChI: 1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key: AGOYDEPGAOXOCK-KCBOHYOISA-N
Quality Level:
200
Assay:
≥95% (HPLC)
form:
powder
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteria
Mode of action:
protein synthesis | interferes
SMILES string:
O[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
InChI:
1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key:
AGOYDEPGAOXOCK-KCBOHYOISA-N
Quality Level: 200
Assay: ≥93% (UV)
form: powder
antibiotic activity spectrum: __
Mode of action: __
SMILES string: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
InChI: __
InChI key: __
Quality Level:
200
Assay:
≥93% (UV)
form:
powder
antibiotic activity spectrum:
__
Mode of action:
__
SMILES string:
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
InChI:
__
InChI key:
__
Quality Level: 200
Assay: __
form: purified powder
antibiotic activity spectrum: __
Mode of action: __
SMILES string: CC(=O)N[C@@H]1[C@H](O)O[C@@H](CO)[C@H](O)[C@H]1O
InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4?,5?,6?,7?,8-/m1/s1
InChI key: OVRNDRQMDRJTHS-WTZNIHQSSA-N
Quality Level:
200
Assay:
__
form:
purified powder
antibiotic activity spectrum:
__
Mode of action:
__
SMILES string:
CC(=O)N[C@@H]1[C@H](O)O[C@@H](CO)[C@H](O)[C@H]1O
InChI:
1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4?,5?,6?,7?,8-/m1/s1
InChI key:
OVRNDRQMDRJTHS-WTZNIHQSSA-N
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
antibiotic activity spectrum: __
Mode of action: __
SMILES string: CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI: 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key: __
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
antibiotic activity spectrum:
__
Mode of action:
__
SMILES string:
CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI:
1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key:
__