Chromomycin A₃
from Streptomyces griseus, ≥95% (HPLC), powder, anti-bacterial, anti-fungal and antitumor
Manufacturer: Sigma Aldrich
CAS Number: 7059-24-7
Synonym(S): Aburamycin B, CMA3, NSC 58514
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | C2659-5-MG | In Stock | ₹ 37,671.00 |
| 10 MG | C2659-10-MG | In Stock | ₹ 44,101.05 |
C2659 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 37,671.00
GST (18%): ₹ 6,780.78
Total Price: ₹ 44,451.78
product name
Chromomycin A3 from Streptomyces griseus, ≥95% (HPLC)
Quality Level
200
Assay
≥95% (HPLC)
form
powder
antibiotic activity spectrum
Gram-positive bacteriafungineoplastics
Mode of action
DNA synthesis | interferes
storage temp.
−20°C
SMILES string
CO[C@H]1[C@@H](O)CC(O[C@H]1C)O[C@H]2CC(O[C@@H](C)[C@H]2OC(C)=O)Oc3cc4cc5C[C@@H]([C@@H](OC)C(=O)[C@@H](O)[C@H](C)O)[C@H](OC6C[C@@H](OC7C[C@H](OC8C[C@](C)(O)[C@@H](OC(C)=O)[C@H](C)O8)[C@@H](O)[C@H](C)O7)[C@H](O)[C@@H](C)O6)C(=O)c5c(O)c4c(O)c3C
InChI
1S/C57H82O26/c1-21-34(79-40-19-37(53(26(6)75-40)77-28(8)59)82-38-16-33(61)52(70-11)25(5)74-38)15-31-13-30-14-32(54(71-12)51(68)46(63)22(2)58)55(50(67)44(30)49(66)43(31)45(21)62)83-41-18-35(47(64)24(4)73-41)80-39-17-36(48(65)23(3)72-39)81-42-20-57(10,69)56(27(7)76-42)78-29(9)60/h13,15,22-27,32-33,35-42,46-48,52-56,58,61-66,69H,14,16-20H2,1-12H3/t22-,23-,24+,25-,26-,27-,32-,33-,35+,36-,37-,38?,39?,40?,41?,42?,46-,47+,48-,52+,53+,54+,55-,56-,57-/m0/s1
InChI key
ZYVSOIYQKUDENJ-MTPXVABGSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Chromomycin A3 from Streptomyces griseus >=95% (HPLC) | 7059-24-7 | MFCD00043151 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 32,072.17 | |
 | Chromomycin A₃ | Sigma Aldrich | ₹ 37,671.00 - ₹ 44,101.05 | |
 | 7059-24-7 | Chromomycin A3 | A2B Chem | -- |
Related Products
Description
- General description: Chemical structure: aureolic acid
- Application: Chromomycin A3 from Streptomyces griseus has been used as a reagent in flow sorting.[1] It has also been used to stain spermatozoa to evaluate the sperm nuclear chromatin integrity.[2]
- Biochem/physiol Actions: Chromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities.[3] It serves as a fluorescent DNA stain.[4] It is useful for the detection of protamine deficiency in sperm chromatin. The compound blocks macromolecule synthesis by a specific, reversible interaction with DNA in the presence of bivalent metal ions. Binding to DNA minor groove mediates an efficient competitive inhibition of DNA gyrase and significantly affects topoisomerase II activity.
- Features and Benefits: This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
product name: Chromomycin A3 from Streptomyces griseus, ≥95% (HPLC)
Quality Level: 200
Assay: ≥95% (HPLC)
form: powder
antibiotic activity spectrum: Gram-positive bacteriafungineoplastics
Mode of action: DNA synthesis | interferes
storage temp.: −20°C
SMILES string: CO[C@H]1[C@@H](O)CC(O[C@H]1C)O[C@H]2CC(O[C@@H](C)[C@H]2OC(C)=O)Oc3cc4cc5C[C@@H]([C@@H](OC)C(=O)[C@@H](O)[C@H](C)O)[C@H](OC6C[C@@H](OC7C[C@H](OC8C[C@](C)(O)[C@@H](OC(C)=O)[C@H](C)O8)[C@@H](O)[C@H](C)O7)[C@H](O)[C@@H](C)O6)C(=O)c5c(O)c4c(O)c3C
InChI: 1S/C57H82O26/c1-21-34(79-40-19-37(53(26(6)75-40)77-28(8)59)82-38-16-33(61)52(70-11)25(5)74-38)15-31-13-30-14-32(54(71-12)51(68)46(63)22(2)58)55(50(67)44(30)49(66)43(31)45(21)62)83-41-18-35(47(64)24(4)73-41)80-39-17-36(48(65)23(3)72-39)81-42-20-57(10,69)56(27(7)76-42)78-29(9)60/h13,15,22-27,32-33,35-42,46-48,52-56,58,61-66,69H,14,16-20H2,1-12H3/t22-,23-,24+,25-,26-,27-,32-,33-,35+,36-,37-,38?,39?,40?,41?,42?,46-,47+,48-,52+,53+,54+,55-,56-,57-/m0/s1
InChI key: ZYVSOIYQKUDENJ-MTPXVABGSA-N
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