Description

• General description: This Snap-N-Spike® Reference Solution is suitable for use in LC/MS or GC/MS applications from clinical toxicology to dietary supplement testing. Caffeine belongs to the class of active alkaloid compounds, mainly found in the leaves, fruits, and seeds of about 63 plant species. Coffee beans are the primary source of caffeine, in addition to tea leaves, chocolates, and energy drinks soft drinks. It is a central nervous system stimulant and acts by increasing alertness and reducing sleep.
• Application: The Certified Reference Material (CRM) in solution can also be used as follows:To determine caffeine content in an aqueous solution of green coffee beans by two methods based on Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) and fluorescence spectrophotometryExtraction of caffeine by automated homogeneous liquid-liquid microextraction (A-HLLME) from five different beverage samples for its quantification by high-performance liquid chromatography combined with UV detectionSimultaneous estimation of caffeine and chlorogenic acids in ground green coffee samples by a UV/Vis spectrometric methodMulti-residue determination of caffeine and paracetamol by square-wave voltammetry using poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode (poly(AHNSA)/GCE in coca-cola, pepsi, and tea samplesCyclic voltammetric and differential pulse voltammetric based detection and quantitative analysis of paracetamol, tryptophan, and caffeine, both separately and simultaneously, using an electrochemical sensor founded on tin sulfide (SnS)-titanium dioxide (TiO2)-graphene oxide (GO) composite modified glassy carbon electrode
• Features and Benefits: Fully characterized under ISO/IEC 17025 and ISO 17034 accreditationAccompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability Rigorously tested through real-time stability studies to ensure accuracy and shelf life Gravimetrically prepared using qualified precision balances to ensure minimal uncertaintyFlame sealed under argon into ampoules for long-term shelf lifeOffered in a convenient, DEA-exempt format to improve laboratory efficiency
• Legal Information: CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany