Description

• General description: This Certified Reference Material is widely used in forensic analysis and clinical toxicology applications to determine blood alcohol content.Ethyl-β-D-glucuronide (EtG) is a water-soluble and stable metabolite of ethanol, used as a routine biomarker in alcohol abuse monitoring. A very small fraction of ethanol undergoes degradation to EtG, and it can be detected in body fluids as well as hair.[1]
• Application: The certified reference solution (CRM) in solution can also be used as follows:Multi-residue analysis of different alcohol metabolites in human blood plasma and urine samples by ultra-high performance liquid chromatography (UHPLC) combined with tandem mass spectrometry (MS/MS)[2]Optimization of a supercritical fluid chromatography-tandem mass spectrometric (SFC-MS/MS) method for the separation and quantification of highly polar drugs and their metabolites using an ion-exchange stationary phase from human urine samplesEvaluation of a paired ion electrospray ionization mass spectrometric (PIESI-MS) approach coupled with high performance liquid chromatographic (HPLC) procedure for the detection and measurement of drug metabolites in urine samples[3]Assess the impact of sample preparation of hair samples on the quantitative analysis of ethyl-β-D-glucuronide by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry[4]Analysis of ethyl-β-D-glucuronide as a urinary biomarker in human urine samples by a benchtop gas chromatograph coupled with a mass spectrometer (GC-MS)[1]
• Features and Benefits: Fully characterized under ISO/IEC 17025 and ISO 17034 accreditationAccompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceabilityRigorously tested through real-time stability studies to ensure accuracy and shelf lifeGravimetrically prepared using qualified precision balances to ensure minimal uncertaintyFlame sealed under argon into ampoules for long-term shelf lifeOffered in a convenient, DEA-exempt format to improve laboratory efficiency
• Legal Information: CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany