MilliporeSigma™ Upstate™ CTCFα, Mouse monoclonal, ChIP Validated Antibody and Primer Set
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 17-100-44MI-Each-of-1 | In Stock | ₹ 53,561.42 |
17-100-44MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,561.42
GST (18%): ₹ 9,641.056
Total Price: ₹ 63,202.476
Antigen
CTCFα
Classification
Monoclonal
Formulation
Anti-CTCF, (mouse monoclonal IgG1κ. One vial containing 50μg of protein G purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide, before the addition of glycerol to 30%. Normal Mouse IgG. Two vials containing 25μg purified IgG in 25μL storage buffer containing 0.1% sodium azide. ChIP Primers, Human H19 ICR. One vial containing 75μL of 5μM of each primer specific for human H19 internal control region. FOR: CCC ATC TTG CT GACC TCAC; REV: AGA CCT GGG ACG TTT CTG TG
Gene Symbols
CTCF
Immunogen
His-tagged recombinant protein corresponding to human CTCF.
Quantity
25 Assays
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_006556.1
Includes
The ChIPAb+ CTCF set includes the CTCF antibody, a negative control antibody (normal mouse IgG) and qPCR primers which amplify a 165bp region of human H19 internal control region.
Content And Storage
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype
IgG1 κ
Applications
Multiplex, Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Immunoassay, Western Blot
Conjugate
Unconjugated
Gene Accession No.
P49711
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes CTCF, Mr ∽130kDa.
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects CTCFα Clone: in Human samples, and it is validated for Chromatin Immunoprecipitation, Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Multiplexing, Western Blotting CTCF, also known as CCCTC-binding factor, contains 11 zinc finger (ZF) binding domains that allow it to bind different DNA target sequences and proteins
- This multifunctional protein can act as a transcriptional activator or repressor
- As a transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene
- It also binds to the PLK and PIM1 promoters
- CTCF may prevent the access of transcriptional activators to enhancers
- CTCF also acts as a transcriptional activator of APP
- It is involved in different aspects of gene regulation including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting
- Mutations of CTCF in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms tumors, suggesting a role for CTCF may as a tumor suppressor.
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Antigen: CTCFα
Classification: Monoclonal
Formulation: Anti-CTCF, (mouse monoclonal IgG1κ. One vial containing 50μg of protein G purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide, before the addition of glycerol to 30%. Normal Mouse IgG. Two vials containing 25μg purified IgG in 25μL storage buffer containing 0.1% sodium azide. ChIP Primers, Human H19 ICR. One vial containing 75μL of 5μM of each primer specific for human H19 internal control region. FOR: CCC ATC TTG CT GACC TCAC; REV: AGA CCT GGG ACG TTT CTG TG
Gene Symbols: CTCF
Immunogen: His-tagged recombinant protein corresponding to human CTCF.
Quantity: 25 Assays
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_006556.1
Includes: The ChIPAb+ CTCF set includes the CTCF antibody, a negative control antibody (normal mouse IgG) and qPCR primers which amplify a 165bp region of human H19 internal control region.
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgG1 κ
Applications: Multiplex, Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Immunoassay, Western Blot
Conjugate: Unconjugated
Gene Accession No.: P49711
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes CTCF, Mr ∽130kDa.
Target Species: Human
Form: Purified
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Includes: __
Content And Storage: __
Isotype: __
Applications: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Target Species: __
Form: __
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Includes: __
Content And Storage: __
Isotype: __
Applications: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Target Species: __
Form: __
