17-102-38MI

MilliporeSigma™ Upstate™ HDAC3 Mouse monoclonal, ChIP Validated Antibody and Primer Set

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 17-102-38MI-Each-of-1 In Stock ₹ 52,449.99

17-102-38MI - Each of 1

₹ 52,449.99

In Stock

Quantity

1

Base Price: ₹ 52,449.99

GST (18%): ₹ 9,440.998

Total Price: ₹ 61,890.988

Antigen

HDAC3

Classification

Monoclonal

Formulation

Anti-HDAC3 (mouse monoclonal). One vial containing 100μg of protein G purified monoclonal in buffer containing 0.02M phosphate buffer (pH 7.6), 0.25M NaCl, 0.1% sodium azide and 30% glycerol. Concentration: 1mg/mL. Normal Mouse IgG. One vial containing 125μg of purified mouse IgG in 125μL of storage buffer containing 0.1% sodium azide. ChIP Primers, p21. One vial containing 75μL of each primer (5μM) specific for a region of the human p21 (WAF1/CIP1/CDKN1A) promoter. FOR: CCC ACA GCA GAG GAG AAA GAA; REV: CTG GAA ATC TCT GCC CAG ACA

Gene Symbols

HDAC3, SMAP45, HD3, RPD3, RPD3-2

Immunogen

peptide (NEFYDGDHDNDKESDVEI) corresponding to amino acids 411-428 of human HDAC3

Regulatory Status

RUO

Primary or Secondary

Primary

Includes

This ChIPAb+ HDAC3 -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage

-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype

IgG2a

Applications

ChIP Assay, Western Blot

Conjugate

Unconjugated

Gene Accession No.

O15379

Host Species

Mouse

Quantity

25 Assays

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NM_003883

Target Species

Bovine, Hamster, Human, Mouse

Form

Purified

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Description

  • Specifically detects HDAC3 Clone: in Bovine, Hamster, Human, Mouse samples, and it is validated for ChIP, Western Blotting Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events
  • Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA
  • HDAC3 belongs to the histone deacetylase/acuc/apha family
  • It has histone deacetylase activity and represses transcription when tethered to a promoter
  • It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1
  • This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis
  • HDAC3 is regarded as a potential tumor suppressor gene.

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MilliporeSigma™

17-102-38MI

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Antigen:
HDAC3

Classification:
Monoclonal

Formulation:
Anti-HDAC3 (mouse monoclonal). One vial containing 100μg of protein G purified monoclonal in buffer containing 0.02M phosphate buffer (pH 7.6), 0.25M NaCl, 0.1% sodium azide and 30% glycerol. Concentration: 1mg/mL. Normal Mouse IgG. One vial containing 125μg of purified mouse IgG in 125μL of storage buffer containing 0.1% sodium azide. ChIP Primers, p21. One vial containing 75μL of each primer (5μM) specific for a region of the human p21 (WAF1/CIP1/CDKN1A) promoter. FOR: CCC ACA GCA GAG GAG AAA GAA; REV: CTG GAA ATC TCT GCC CAG ACA

Gene Symbols:
HDAC3, SMAP45, HD3, RPD3, RPD3-2

Immunogen:
peptide (NEFYDGDHDNDKESDVEI) corresponding to amino acids 411-428 of human HDAC3

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ HDAC3 -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
IgG2a

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
O15379

Host Species:
Mouse

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NM_003883

Target Species:
Bovine, Hamster, Human, Mouse

Form:
Purified

Img

MilliporeSigma™

17-102-41MI

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Antigen:
Acetyl-Histone H3 (Lys9/18)

Classification:
Polyclonal

Formulation:
Anti-Acetyl-Histone H3 (Lys9/18) (rabbit polyclonal). One vial containing 25μL of rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%. Normal Rabbit Serum. One vial containing 25μL of antiserum containing 0.05% sodium azide. Control Primers, human GAPDH promoter. One vial containing 75μL of 5μM of each primer specific for human GAPDH. FOR: TAC TAG CGG TTT TAC GGG CG; REV: TCG AAC AGG AGG AGC AGA GAG CGA

Gene Symbols:
H3F3A, MGC87783, H3.3A, MGC87782, H3F3, H3.3B, H3F3B

Immunogen:
KLH-conjugated synthetic peptide (..ARAcKSTGGKAPRAcKQL..) in which AcK corresponds to acetyl-lysine at residue 9 and 18 of human Histone H3.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ Acetyl-Histone H3 (Lys9/18) -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
__

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q16695

Host Species:
Rabbit

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NM_003493

Target Species:
Bovine, Human, Mouse, S. cerevisiae, Yeast

Form:
Serum

Img

MilliporeSigma™

17-102-42MI

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Antigen:
Trimethyl-Histone H3 (Lys9)α

Classification:
Monoclonal

Formulation:
Anti-Trimethyl-Histone H3 (Lys9) (mouse monoclonal). One vial containing 25μL of purified mouse monoclonal IgG1 in PBS with 0.05% sodium azide before the addition of glycerol to 30%. Normal Mouse IgG. One vial containing 25μg of purified IgG in 25μL of storage buffer containing 0.1% sodium azide. Control Primers, ZNF554. One vial containing 75μL of 5μM of each primer specific for the 3’ end of human ZNF554. FOR: CGG GGA AAA GCC CTA TAA AT; REV: TCC ACA TTC ACT GCA TTC GT

Gene Symbols:
H3., H3/g, H3/t, H3FT, H3T, H3t, MGC126886, MGC126888, OTTHUMP00000037945

Immunogen:
KLH-conjugated synthetic peptide corresponding to human Histone H3 trimethylated on Lys9.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ Trimethyl-Histone H3 (Lys9) -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
2°C to 8°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at -20°C; Avoid repeated freeze/thaw cycles

Isotype:
IgG1 κ

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q16695

Host Species:
Mouse

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NM_003493

Target Species:
Human, Vertebrates

Form:
Purified

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MilliporeSigma™

17-102-45MI

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Antigen:
Histone H3.3

Classification:
Polyclonal

Formulation:
Anti-Histone H3.3 (rabbit polyclonal). One vial containing 50μg of purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide before the addition of glycerol to 30%. Concentration: 0.7mg/mL. Normal Rabbit IgG. One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. Control Primers, GAPDH Coding Region D2 Human. One vial containing 75μL of 5μM of each primer specific for human GAPDH coding region. FOR: GCC ATG TAG ACC CCT TGA AGA G; REV: ACT GGT TGA GCA CAG GGT ACT TTA T

Gene Symbols:
H3F3A, H3.3A, H3F3, PP781, H3F3B, H3.3B

Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3.3.

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ Histone H3.3 -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
__

Applications:
ChIP Assay, Dot Blot, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
P84243

Host Species:
Rabbit

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_002098

Target Species:
Human, Mouse

Form:
__