17-102-60MI

MilliporeSigma™ Upstate™ N-CoR, Rabbbit Polyclonal, ChIP Validated Antibody and Primer Set

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 17-102-60MI-Each-of-1 In Stock ₹ 53,561.42

17-102-60MI - Each of 1

₹ 53,561.42

In Stock

Quantity

1

Base Price: ₹ 53,561.42

GST (18%): ₹ 9,641.056

Total Price: ₹ 63,202.476

Antigen

N-CoR

Classification

Polyclonal

Formulation

Anti-N-CoR (Rabbit Polyclonal). One vial containing 75μg of affinity purified polyclonal in buffer containing 0.1M Tris-glycine (pH 7.4) and 150mM NaCl with 0.05% sodium azide before the addition of 30% glycerol. Concentration: 0.7mg/mL. Normal Rabbit IgG One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, p21. One vial containing 75μL of each primer (5μM) specific for the human p21 (WAF1/CIP1/CDKN1A) promoter. FOR: CCC ACA GCA GAG GAG AAA GAA; REV: CTG GAA ATC TCT GCC CAG ACA

Gene Symbols

Ncor1, Rxrip13

Immunogen

KLH-conjugated linear peptide corresponding to a region between amino acids 1510 and 1540 of the N-CoR protein.

Quantity

25 Assays

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_035438

Target Species

Human, Mouse

Applications

ChIP Assay, Western Blot

Conjugate

Unconjugated

Gene Accession No.

Q60974.

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Includes

This ChIPAb+ N-CoR -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage

-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

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Description

  • Specifically detects N-CoR Clone: in Human, Mouse samples, and it is validated for ChIP, Western Blotting In the absence of ligands, the corepressor N-CoR represses nuclear hormone receptor-mediated gene transcription
  • In the presence of ligands, these hormone receptors activate gene expression and play critical roles in development, growth, and homeostasis
  • N-Cor-mediated transcriptional repression is facilitated through the formation of histone deacetylase (HDACs) N-CoR complexes or by conjugation from small ubiquitin-like modifier 1 (SUMO-1)
  • It is shown that the SANT1 domain of N-CoR serves as a binding region for SUMO-E2 conjugating enzyme Ubc9 and SUMO-E3 ligase Pias1, which is necessary for N-CoR-mediated repression of respective reporter genes
  • SUMOylation-deficient N-COR knockout mice display a signification reduction in the repression of gene transcription and result in defects involving the differentiation and development of neural cells into erythrocytes and thymocytes.

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MilliporeSigma™

17-102-60MI

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Antigen:
N-CoR

Classification:
Polyclonal

Formulation:
Anti-N-CoR (Rabbit Polyclonal). One vial containing 75μg of affinity purified polyclonal in buffer containing 0.1M Tris-glycine (pH 7.4) and 150mM NaCl with 0.05% sodium azide before the addition of 30% glycerol. Concentration: 0.7mg/mL. Normal Rabbit IgG One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, p21. One vial containing 75μL of each primer (5μM) specific for the human p21 (WAF1/CIP1/CDKN1A) promoter. FOR: CCC ACA GCA GAG GAG AAA GAA; REV: CTG GAA ATC TCT GCC CAG ACA

Gene Symbols:
Ncor1, Rxrip13

Immunogen:
KLH-conjugated linear peptide corresponding to a region between amino acids 1510 and 1540 of the N-CoR protein.

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_035438

Target Species:
Human, Mouse

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q60974.

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ N-CoR -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Img

MilliporeSigma™

17-102-62MI

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Antigen:
JMJD1C

Classification:
Polyclonal

Formulation:
Anti-JMJD1C (rabbit polyclonal). One vial containing 50μL of purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide before the addition of glycerol to 30%. Concentration: 0.7mg/mL. Normal Rabbit IgG. One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, human β-globin. One vial containing 75μL of each primer (5μM) specific for the human β-globin promoter. FOR: AGG ACA GGT ACG GCT GTC ATC; REV: TTT ATG CCC AGC CCT GGC TC

Gene Symbols:
TRIP8, RP11-10C13.2, JMJD1C, JHDM2C

Immunogen:
KLH-conjugated linear peptide corresponding to human JMJD1C.

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_116165

Target Species:
Chimpanzee, Human, Rabbit, Rhesus Monkey

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q15652

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ JMJD1C -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Img

MilliporeSigma™

17-102-63MI

--


Antigen:
JMJD6

Classification:
Polyclonal

Formulation:
Anti-JMJD6 (rabbit polyclonal). One vial containing 50μL of purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide before the addition of glycerol to 30%. Concentration: 0.7mg/mL. Normal Rabbit IgG. One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, human β-globin. One vial containing 75μL of each primer (5μM) specific for the human β-globin promoter. FOR: AGG ACA GGT ACG GCT GTC ATC; REV: TTT ATG CCC AGC CCT GGC TC

Gene Symbols:
JMJD6, PTDSR1, PTDSR, PSR

Immunogen:
Linear peptide corresponding to human JMJD6.

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_001074930

Target Species:
Human

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q6NYC1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ JMJD6 -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

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17-102-64MI

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Antigen:
JHDM1B

Classification:
Polyclonal

Formulation:
Anti-JHDM1B (Rabbit Polyclonal). One vial containing 50μL of purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4) and 150mM NaCl and 0.05% sodium azide before the addition of glycerol to 30%. Concentration: 0.7mg/mL. Normal Rabbit IgG. One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, human β-globin. One vial containing 75μL of each primer (5μM) specific for the human β-globin promoter. FOR: AGG ACA GGT ACG GCT GTC ATC; REV: TTT ATG CCC AGC CCT GGC TC

Gene Symbols:
KDM2B, CXXC2, FBXL10, JHDM1B, PCCX2, Fbl10, FBL10

Immunogen:
KLH-conjugated linear peptide corresponding to human JHDM1B.

Quantity:
25 Assays

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_115979

Target Species:
Chimpanzee, Equine, Human, Mouse, Porcine, Rabbit, Rat

Applications:
ChIP Assay, Dot Blot, Western Blot

Conjugate:
Unconjugated

Gene Accession No.:
Q8NHM5

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Includes:
This ChIPAb+ JHDM1B -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.

Content And Storage:
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles