01-670-723

CD2 Monoclonal Antibody (T6.3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-723-Each-of-1 In Stock ₹ 36,790.80

01-670-723 - Each of 1

₹ 36,790.80

In Stock

Quantity

1

Base Price: ₹ 36,790.80

GST (18%): ₹ 6,622.344

Total Price: ₹ 43,413.144

Antigen

CD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

P06729

Gene Symbols

CD2

Immunogen

T Lymphocytes activated by mixed lymphocyte culture

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

T6.3

Conjugate

Unconjugated

Gene

CD2

Gene Alias

Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-670-723

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Antigen:
CD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
T Lymphocytes activated by mixed lymphocyte culture

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
T6.3

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-670-725

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
T Lymphocytes activated by mixed lymphocyte culture

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
T6.3

Conjugate:
Biotin

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-670-726

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
T Lymphocytes activated by mixed lymphocyte culture

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
T6.3

Conjugate:
PE

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-670-727

--


Antigen:
CD2/CD7

Classification:
Cocktail

Concentration:
__

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729, P09564

Gene Symbols:
CD2, CD7

Immunogen:
T lymphocytes activated by mixed lymphocyte culture and T-acute lymphoblastic leukemia (T-ALL) cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
T6.3, MG34, MG34

Conjugate:
PE

Gene:
CD7

Gene Alias:
2CD2 antigen; CD2; CD2 molecule; CD7; CD7 antigen (p41); CD7 molecule; Erythrocyte receptor; GP40; LEU-9; LFA-2; LFA-3 receptor; p41 protein; Rosette receptor; SRBC; T11; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; Tp40; TP41

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914, 924

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid