01-670-725

CD2 Monoclonal Antibody (T6.3), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-670-725-Each-of-1 In Stock ₹ 36,619.68

01-670-725 - Each of 1

₹ 36,619.68

In Stock

Quantity

1

Base Price: ₹ 36,619.68

GST (18%): ₹ 6,591.542

Total Price: ₹ 43,211.222

Antigen

CD2

Classification

Monoclonal

Conjugate

Biotin

Gene

CD2

Gene Alias

Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

914

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Flow Cytometry

Clone

T6.3

Formulation

PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.

P06729

Gene Symbols

CD2

Immunogen

T Lymphocytes activated by mixed lymphocyte culture

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

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Thermo Scientific

01-670-725

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Antigen:
CD2

Classification:
Monoclonal

Conjugate:
Biotin

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry

Clone:
T6.3

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
T Lymphocytes activated by mixed lymphocyte culture

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

01-670-726

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
PE

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry

Clone:
T6.3

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
T Lymphocytes activated by mixed lymphocyte culture

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

01-670-727

--


Antigen:
CD2/CD7

Classification:
Cocktail

Conjugate:
PE

Gene:
CD7

Gene Alias:
2CD2 antigen; CD2; CD2 molecule; CD7; CD7 antigen (p41); CD7 molecule; Erythrocyte receptor; GP40; LEU-9; LFA-2; LFA-3 receptor; p41 protein; Rosette receptor; SRBC; T11; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; Tp40; TP41

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914, 924

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
T6.3, MG34, MG34

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729, P09564

Gene Symbols:
CD2, CD7

Immunogen:
T lymphocytes activated by mixed lymphocyte culture and T-acute lymphoblastic leukemia (T-ALL) cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

01-670-728

--


Antigen:
CD2/CD7

Classification:
Cocktail

Conjugate:
PE

Gene:
CD7

Gene Alias:
2CD2 antigen; CD2; CD2 molecule; CD7; CD7 antigen (p41); CD7 molecule; Erythrocyte receptor; GP40; LEU-9; LFA-2; LFA-3 receptor; p41 protein; Rosette receptor; SRBC; T11; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; Tp40; TP41

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
914, 924

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
T6.3, MG34, MG34

Formulation:
PBS with 0.2% carrier protein and 0.08% sodium azide

Gene Accession No.:
P06729, P09564

Gene Symbols:
CD2, CD7

Immunogen:
T lymphocytes activated by mixed lymphocyte culture and T-acute lymphoblastic leukemia (T-ALL) cells

Quantity:
50 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a